Losardil Tablet 100 mg contains Losartan Potassium, a high-potency angiotensin II receptor blocker (ARB) widely used for managing hypertension, cardiovascular risk reduction, and renal protection in patients with type 2 diabetes and proteinuria. By effectively controlling high blood pressure, Losardil 100 mg helps lower the risk of stroke, heart attack, heart failure, and kidney damage, making it an essential therapy for patients with elevated cardiovascular risk.

Losartan works by blocking the AT1 receptors for angiotensin II, a hormone that causes blood vessels to constrict and stimulates aldosterone release. This leads to vasodilation, reduced blood pressure, decreased fluid retention, and improved heart function. In addition, it helps protect the kidneys in diabetic patients by reducing proteinuria and glomerular pressure.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Losardil Tablet 100 mg provides therapeutic effects through:

• Angiotensin II receptor blockade: Prevents vasoconstriction by selectively blocking AT1 receptors, resulting in relaxation of blood vessels.

• Vasodilation and blood pressure reduction: Decreases systemic vascular resistance, lowering blood pressure effectively.

• Renal protection: Reduces intraglomerular pressure, decreases proteinuria, and slows progression of diabetic nephropathy.

• Cardiovascular benefits: Reduces workload on the heart, minimizing the risk of heart failure, stroke, and other complications of hypertension.

This mechanism ensures sustained blood pressure control, improved cardiovascular health, and kidney protection in at-risk patients.

Indications

Losardil Tablet 100 mg is indicated for:

• Hypertension: For adults requiring stronger blood pressure control, either as monotherapy or in combination with other antihypertensive agents.

• Diabetic nephropathy: Reduces proteinuria and slows kidney damage in patients with type 2 diabetes.

• Cardiovascular risk reduction: Prevents stroke, myocardial infarction, and heart failure in patients with elevated blood pressure.

It is not suitable for pregnant or breastfeeding women, or patients with severe liver disease or hypersensitivity to Losartan.

Dosage and Administration

• The standard adult dose is 100 mg once daily, taken orally with or without food.

• Tablets should be swallowed whole with water.

• Dosage may be adjusted depending on blood pressure response, kidney function, and physician recommendation.

• Regular monitoring of blood pressure, renal function, and serum electrolytes is recommended, especially during dose escalation.

• Combine therapy with dietary modifications, exercise, and salt restriction for optimal outcomes.

Precautions

• Avoid during pregnancy, as Losartan may cause fetal injury or death.

• Caution in patients with renal impairment, low blood pressure, or hyperkalemia.

• Inform your healthcare provider of any other medications being taken, including potassium supplements, diuretics, or NSAIDs.

• Elderly patients may require closer monitoring due to increased sensitivity to blood pressure-lowering effects.

• Discontinue and consult a doctor if severe dizziness, fainting, or swelling occurs.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Dizziness or lightheadedness, particularly after the first dose

• Headache

• Fatigue

• Mild gastrointestinal discomfort, such as nausea or abdominal pain

Rare but serious side effects include:

• Hyperkalemia (elevated potassium)

• Hypotension (excessive blood pressure reduction)

• Worsening kidney function

• Severe allergic reactions (rash, swelling, difficulty breathing)

Seek immediate medical attention if severe or persistent symptoms occur.

Storage

Store below 30°C in a dry place, protected from sunlight and moisture. Keep out of reach of children.

Losardil Tablet 100 mg provides potent blood pressure control, kidney protection, and cardiovascular risk reduction, making it an essential treatment for patients with hypertension and related comorbidities.