Co-dopa CR Tablet 200 mg+50 mg is a prolonged-release formulation containing Levodopa 200 mg and Carbidopa 50 mg, specially designed for the effective management of Parkinson’s disease and Parkinsonism. This controlled-release (CR) tablet provides a steady and sustained release of medication over an extended period, helping maintain more stable dopamine levels in the brain and reducing fluctuations in symptom control.

Parkinson’s disease is a progressive neurological disorder characterized by tremors, rigidity, slowness of movement (bradykinesia), and postural instability. These symptoms occur due to a deficiency of dopamine in the brain. Levodopa is converted into dopamine after crossing the blood-brain barrier, thereby helping restore dopamine levels and improving motor function. Carbidopa works by inhibiting the peripheral breakdown of levodopa before it reaches the brain, enhancing its effectiveness and minimizing side effects such as nausea and vomiting.

The prolonged-release formulation of Co-dopa CR ensures gradual absorption and extended therapeutic action. This helps reduce “wearing-off” effects and provides longer-lasting symptom relief, particularly in patients experiencing motor fluctuations with conventional immediate-release preparations.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Co-dopa CR Tablet is indicated for:

• Parkinson’s disease

• Parkinsonism (including post-encephalitic and toxin-induced Parkinsonism)

• Management of motor fluctuations associated with long-term levodopa therapy

Key Benefits

• Provides sustained and stable dopamine replacement

• Reduces motor fluctuations and “off” periods

• Minimizes nausea and gastrointestinal discomfort due to carbidopa

• Improves mobility, muscle control, and overall quality of life

• Suitable for patients requiring extended symptom control

Dosage and Administration

The dosage of Co-dopa CR Tablet should be individualized according to the patient’s clinical response and physician’s recommendation. The tablet should be swallowed whole with water and should not be crushed or chewed, as this may interfere with the prolonged-release mechanism.

Dose adjustments may be necessary when switching from immediate-release levodopa/carbidopa formulations. Patients should follow their healthcare provider’s instructions carefully for optimal results.

Precautions

• Use with caution in patients with cardiovascular disease, glaucoma, or psychiatric disorders.

• Sudden discontinuation should be avoided as it may lead to serious complications.

• Patients may experience dizziness or drowsiness; caution is advised when driving or operating machinery.

• Regular monitoring is recommended during long-term therapy.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Nausea and vomiting

• Dizziness

• Dyskinesia (involuntary movements)

• Insomnia

• Orthostatic hypotension

Most side effects are dose-related and can be managed with proper medical supervision.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.