Camzoy Capsule 2.5 mg contains Mavacamten, a first-in-class cardiac myosin inhibitor used for the treatment of symptomatic obstructive hypertrophic cardiomyopathy (HCM). It helps improve heart muscle relaxation and reduces excessive contraction of the left ventricle, thereby decreasing left ventricular outflow tract (LVOT) obstruction and improving symptoms such as chest pain, shortness of breath, and exercise intolerance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Mavacamten 2.5 mg
• Dosage Form: Oral capsule

Mechanism of Action

Mavacamten works by selectively inhibiting cardiac myosin ATPase activity. This reduces excessive actin–myosin cross-bridge formation in cardiac muscle, leading to decreased hypercontractility. In obstructive HCM, this results in reduced LVOT obstruction, improved diastolic function, and better overall cardiac performance.

Indications

Camzoy Capsule 2.5 mg is indicated for:

• Symptomatic obstructive hypertrophic cardiomyopathy (oHCM) in adults
• Reduction of LVOT obstruction
• Improvement of exercise capacity and quality of life in HCM patients

Dosage and Administration

• Must be used under the supervision of a qualified cardiologist
• Dose is individualized based on echocardiographic findings and clinical response
• Typically taken once daily
• Regular monitoring of left ventricular ejection fraction (LVEF) is required
• Capsule should be swallowed whole with water

Precautions

• Not recommended in patients with significantly reduced left ventricular ejection fraction
• Requires periodic cardiac imaging (echocardiography) during treatment
• Use with caution in patients with liver impairment
• Avoid during pregnancy unless clearly necessary
• Potential drug interactions with CYP2C19 and CYP3A4 inhibitors or inducers

Side Effects

Common side effects include:

• Dizziness
• Fatigue
• Shortness of breath
• Reduced cardiac function (dose-dependent)

Serious side effects:

• Worsening heart failure
• Significant reduction in ejection fraction
• Cardiac rhythm disturbances (rare)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children
• Do not use after expiry date

Conclusion

Camzoy Capsule 2.5 mg (Mavacamten) is an advanced cardiac therapy designed for the management of obstructive hypertrophic cardiomyopathy. It improves cardiac function and reduces symptoms by targeting abnormal heart muscle contractility, under strict cardiology supervision.