BrimoPres Eye Drop combines Brimonidine Tartrate 0.2%, an alpha-2 adrenergic agonist, with Timolol Maleate 0.5%, a non-selective beta-blocker, to provide dual-action management of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension. This fixed-dose combination works synergistically to lower IOP by both decreasing aqueous humor production and enhancing fluid outflow, offering effective long-term protection for the optic nerve.

The combination therapy is ideal for patients who require more than one mechanism to control IOP, reducing the number of eye drops needed and improving adherence to treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Effectively reduces elevated intraocular pressure through dual mechanisms
• Protects the optic nerve and helps prevent vision loss
• Reduces the number of daily doses compared to separate therapy
• Convenient combination therapy for long-term glaucoma management
• Topical application ensures localized effect with minimal systemic exposure

Indications

BrimoPres Eye Drop 0.2% + 0.5% is indicated for:

• Open-angle glaucoma
• Ocular hypertension
• Patients requiring dual therapy to achieve optimal intraocular pressure control

Mechanism of Action

• Brimonidine Tartrate (0.2%): Activates alpha-2 adrenergic receptors to reduce aqueous humor production and increase uveoscleral outflow.
• Timolol Maleate (0.5%): Non-selective beta-blocker that reduces aqueous humor production by blocking beta-adrenergic receptors in the ciliary body.
• The combination provides additive IOP-lowering effects, improving efficacy and reducing the risk of optic nerve damage.

Dosage and Administration

• Instill 1 drop into the affected eye(s) twice daily or as prescribed by a physician
• Wash hands before administration and avoid touching the dropper tip to the eye
• Remove contact lenses prior to instillation; they can be reinserted 15 minutes after use
• Use consistently at the same times each day for optimal results

Side Effects

Common side effects:

• Eye redness, stinging, or burning
• Temporary blurred vision
• Mild itching or irritation

Rare side effects:

• Allergic reactions including swelling or rash around the eye
• Slow heart rate, low blood pressure, or dizziness
• Fatigue or dry mouth

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• For ophthalmic use only
• Avoid contamination of the dropper tip
• Use with caution in patients with cardiovascular, respiratory, or cerebrovascular conditions
• Discontinue and consult a physician if severe irritation or vision changes occur

Contraindications

• Hypersensitivity to Brimonidine Tartrate, Timolol Maleate, or any component of the formulation
• Severe bradycardia, heart block, or cardiac failure
• Severe asthma or chronic obstructive pulmonary disease without medical supervision

Storage Instructions

• Store below 30°C in a dry place
• Protect from light and contamination
• Keep out of reach of children.