Avloclav Suspension is a broad-spectrum oral antibiotic containing Amoxicillin 125 mg and Clavulanic Acid 31.25 mg per 5 ml. This combination is designed to treat bacterial infections, including those caused by beta-lactamase-producing bacteria that are resistant to amoxicillin alone. Amoxicillin works by inhibiting bacterial cell wall synthesis, while Clavulanic Acid blocks bacterial beta-lactamase enzymes, enhancing the effectiveness of amoxicillin. This pediatric-friendly suspension is especially useful for children or patients who have difficulty swallowing tablets.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Amoxicillin: 125 mg – penicillin-type antibiotic that inhibits bacterial cell wall synthesis
• Clavulanic Acid: 31.25 mg – beta-lactamase inhibitor that protects amoxicillin from enzymatic degradation

Mechanism of Action

• Amoxicillin: Targets bacterial penicillin-binding proteins (PBPs), disrupting cell wall synthesis and leading to bacterial death
• Clavulanic Acid: Inhibits beta-lactamase enzymes produced by resistant bacteria, allowing amoxicillin to remain effective
• Provides enhanced antibacterial activity against both Gram-positive and Gram-negative bacteria

Indications

Avloclav Suspension is indicated for the treatment of:

• Respiratory tract infections: bronchitis, pneumonia, sinusitis
• Ear, nose, and throat infections: otitis media, tonsillitis, pharyngitis
• Urinary tract infections
• Skin and soft tissue infections: abscesses, cellulitis, wound infections
• Dental infections and other mild to moderate bacterial infections

Dosage and Administration

• Shake the bottle well before use to ensure a uniform suspension
• Use the measuring cup or syringe provided for accurate dosing
• Typical pediatric dosage: 20–40 mg/kg/day (based on amoxicillin component) in divided doses every 8–12 hours, as prescribed by a physician
• Adults may also use the suspension if tablets are not suitable, according to physician recommendation
• Complete the full course of therapy, even if symptoms improve

Benefits

• Broad-spectrum antibiotic effective against resistant bacterial strains
• Pediatric-friendly oral suspension for easy administration
• Treats respiratory, ear, urinary, skin, and dental infections
• Protects against beta-lactamase-producing bacteria, reducing treatment failure
• Convenient dosing with flexible administration

Possible Side Effects

Common side effects:

• Diarrhea or loose stools
• Nausea and vomiting
• Rash or mild itching

Rare but serious side effects:

• Severe allergic reactions (anaphylaxis, swelling, difficulty breathing)
• Liver enzyme abnormalities or jaundice
• Clostridium difficile-associated diarrhea

Precautions and Warnings

• Contraindicated in patients with penicillin allergy
• Use cautiously in patients with kidney impairment
• Monitor for allergic reactions or severe gastrointestinal symptoms
• Not effective against viral infections
• Inform your physician of all current medications

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral anticoagulants, methotrexate, allopurinol, and other antibiotics
• May reduce effectiveness of oral contraceptives
• Adjust dose in cases of renal impairment

Storage Instructions

• Store the suspension at 15–25°C, protected from light and moisture
• Shake well before each use
• Keep out of reach of children
• Discard the remaining suspension after the expiry date.