Metform Tablet 850 mg contains Metformin Hydrochloride, a widely prescribed oral antidiabetic medication used for the management of type 2 diabetes mellitus. It belongs to the biguanide class of drugs and is considered a first-line treatment for controlling blood glucose levels, particularly in overweight patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Metformin Hydrochloride 850 mg

Mechanism of Action

Metformin works primarily by decreasing glucose production in the liver (hepatic gluconeogenesis), reducing intestinal absorption of glucose, and improving insulin sensitivity. This helps the body utilize insulin more effectively, leading to better blood sugar control without causing significant hypoglycemia when used alone.

Indications

Metform Tablet 850 mg is indicated for:

• Management of type 2 diabetes mellitus
• Improving glycemic control in adults
• Use as monotherapy or in combination with other antidiabetic agents (such as sulfonylureas or insulin)
• Prevention of diabetes complications through better glucose regulation

Dosage and Administration

• The dosage should be individualized based on the patient’s condition and physician’s advice.
• Typically taken with meals to reduce gastrointestinal side effects.
• Tablets should be swallowed whole with water.
• Do not crush or chew unless advised by a healthcare provider.

Benefits

• Effectively lowers blood glucose levels
• Does not usually cause weight gain; may support modest weight loss
• Low risk of hypoglycemia when used alone
• Improves insulin sensitivity
• Helps reduce long-term diabetes-related complications

Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Loss of appetite

Rare but serious side effect:

• Lactic acidosis (a rare but potentially life-threatening condition), especially in patients with kidney impairment

Precautions

• Use with caution in patients with kidney, liver, or heart disease
• Regular monitoring of renal function is recommended
• Avoid excessive alcohol intake as it increases the risk of lactic acidosis
• Inform your doctor before undergoing any imaging procedure requiring contrast dye
• Not recommended in severe renal impairment

Contraindications

• Severe kidney disease
• Acute or chronic metabolic acidosis
• Hypersensitivity to Metformin or any component of the formulation

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Metformin may interact with:

• Other antidiabetic drugs (may increase risk of hypoglycemia)
• Diuretics and corticosteroids (may affect blood glucose control)
• Contrast agents (increase risk of kidney complications)

Storage

• Store in a cool, dry place below 30°C
• Keep away from direct sunlight and moisture
• Keep out of reach of children.