Amotrex Tablet 200 mg contains Metronidazole, a potent antimicrobial and antiprotozoal agent used to treat infections caused by anaerobic bacteria and certain protozoa. It is commonly prescribed for gastrointestinal, gynecological, dental, and skin infections. Metronidazole works by disrupting the DNA synthesis of harmful microorganisms, preventing their growth and helping the body combat infection effectively.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Metronidazole 200 mg

Mechanism of Action

Metronidazole enters bacterial and protozoal cells and inhibits nucleic acid synthesis, which leads to the death of the microorganisms. It is particularly effective against anaerobic bacteria, which thrive in oxygen-deficient environments, such as the gastrointestinal tract, oral cavity, and deep tissue infections.

Indications

Amotrex Tablet 200 mg is indicated for:

• Gastrointestinal infections, including amoebiasis and giardiasis
• Bacterial vaginosis and gynecological infections
• Dental infections and periodontitis
• Skin and soft tissue infections caused by susceptible organisms
• Helicobacter pylori-associated infections (as part of combination therapy)

Dosage and Administration

• Adults: Typically 200–400 mg 2–3 times daily, depending on infection type and severity.
• Children: Dosage is weight-based and should be determined by a physician.
• Take the tablet orally with a full glass of water, preferably after meals to reduce stomach upset.
• Complete the full prescribed course, even if symptoms improve early, to prevent recurrence or resistance.
• Dosage adjustment may be required for patients with liver impairment.

Benefits

• Effectively targets anaerobic bacteria and protozoa
• Helps relieve infection-related symptoms such as pain, inflammation, and diarrhea
• Supports faster recovery and prevents spread of infection
• Convenient tablet form for easy administration
• Can be used in both adults and children under medical supervision

Possible Side Effects

Common side effects may include:

• Nausea or vomiting
• Metallic taste in the mouth
• Abdominal pain or diarrhea
• Headache
• Dizziness

Rare but serious side effects may include peripheral neuropathy, seizures, or severe allergic reactions. Medical attention should be sought if severe symptoms occur.

Precautions and Warnings

• Avoid alcohol during treatment and for at least 48 hours after completion, as it may cause a disulfiram-like reaction (nausea, vomiting, flushing).
• Use cautiously in patients with liver disease, neurological disorders, or blood disorders.
• Consult a physician before use during pregnancy or breastfeeding.
• Inform your healthcare provider about any other medications being taken.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Amotrex Tablet 200 mg may interact with:

• Warfarin (may increase bleeding risk)
• Lithium
• Certain antiepileptic medications
• Alcohol (may trigger adverse reactions)

Storage Instructions

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.