Wella Tablet combines Amitriptyline Hydrochloride (12.5 mg) and Chlordiazepoxide (5 mg) to provide a dual-action therapy for anxiety and depression-related disorders. Amitriptyline, a tricyclic antidepressant, works by modulating neurotransmitters such as serotonin and norepinephrine to improve mood and emotional balance. Chlordiazepoxide, a benzodiazepine, acts as an anxiolytic, reducing tension, agitation, and nervousness.

This combination is particularly useful for patients suffering from mixed anxiety-depressive states, offering both mood stabilization and calming effects in a single tablet for convenient administration.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Wella Tablet 12.5 mg+5 mg is indicated for:

• Treatment of mixed anxiety-depressive disorders
• Management of anxiety with depression or tension
• Short-term relief of agitation and nervousness associated with depression
• Supportive therapy in patients with sleep disturbances due to anxiety or depression

Mechanism of Action

• Amitriptyline Hydrochloride:
  • Inhibits the reuptake of serotonin and norepinephrine, increasing their levels in the synaptic cleft
  • Enhances mood, energy, and emotional stability
  • Reduces physical and emotional symptoms of depression
• Chlordiazepoxide:
  • Potentiates the effect of gamma-aminobutyric acid (GABA) in the brain
  • Produces anxiolytic and sedative effects, reducing nervous tension and restlessness
  • Helps improve sleep quality in anxious patients

The combination provides synergistic benefits, addressing both depressive and anxiety symptoms simultaneously.

Dosage and Administration

• Take Wella Tablet orally, usually once daily or as prescribed by a physician
• May be taken with or without food
• Avoid abrupt discontinuation, especially after long-term use, to prevent withdrawal symptoms
• Dose adjustments may be necessary in elderly patients or those with liver/kidney impairment
• Follow the physician’s instructions carefully for optimal therapeutic effect

Benefits

• Addresses both anxiety and depressive symptoms in one formulation
• Improves mood, sleep, and emotional stability
• Reduces tension, nervousness, and agitation
• Convenient fixed-dose combination simplifies therapy
• Enhances overall quality of life in patients with mixed anxiety-depressive disorders

Side Effects

Common side effects may include:

• Drowsiness or sedation
• Dry mouth, blurred vision
• Constipation or gastrointestinal upset
• Mild dizziness or lightheadedness

Serious but rare side effects:

• Cardiac arrhythmias or palpitations
• Severe allergic reactions
• Confusion, disorientation, or severe mood changes

Consult a physician immediately if serious adverse effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with heart disease, liver or kidney impairment, glaucoma, or history of seizures
• Avoid alcohol or CNS depressants, which may enhance sedative effects
• Not recommended for pregnant or breastfeeding women unless prescribed by a doctor
• Avoid operating machinery or driving until the drug’s effect is known
• Keep out of reach of children

Storage

• Store at below 25°C in a cool, dry place
• Keep the tablet in its original container
• Protect from light and moisture
• Do not use after the expiration date.