Pavigard Tablet 2 mg contains Pitavastatin Calcium, a potent HMG-CoA reductase inhibitor (statin) used to lower cholesterol and triglyceride levels in the blood. By inhibiting the enzyme HMG-CoA reductase, Pitavastatin reduces the synthesis of cholesterol in the liver, leading to decreased levels of low-density lipoprotein cholesterol (LDL-C) and total cholesterol, while modestly increasing high-density lipoprotein cholesterol (HDL-C).

Pavigard Tablet is primarily prescribed for patients with hyperlipidemia or mixed dyslipidemia and is often part of a comprehensive treatment plan that includes diet, exercise, and lifestyle modifications. Its use helps reduce the risk of cardiovascular events, such as heart attacks, strokes, and atherosclerosis-related complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Reduces LDL cholesterol and total cholesterol

• Increases HDL cholesterol to support cardiovascular health

• Helps lower triglycerides, improving overall lipid profile

• Reduces the risk of heart attack, stroke, and cardiovascular disease

• Supports a healthy lifestyle when combined with diet and exercise

• Convenient oral tablet formulation for daily use

Mechanism of Action

Pitavastatin, the active ingredient in Pavigard Tablet, works by:

1. Inhibiting HMG-CoA Reductase:

   • HMG-CoA reductase is a key enzyme in the cholesterol biosynthesis pathway in the liver.

   • By inhibiting this enzyme, Pitavastatin decreases the production of cholesterol.

2. Upregulation of LDL Receptors:

   • Reduced cholesterol synthesis in the liver triggers upregulation of LDL receptors on hepatocytes.

   • This enhances the removal of LDL cholesterol from the bloodstream, lowering circulating levels of “bad” cholesterol.

3. Improvement of Lipid Profile:

   • Pitavastatin effectively lowers LDL-C and total cholesterol, reduces triglycerides, and slightly increases HDL-C, providing a balanced lipid-lowering effect.

   • Helps stabilize atherosclerotic plaques and improves vascular function.

Indications

Pavigard Tablet 2 mg is indicated for:

• Primary hyperlipidemia (elevated LDL cholesterol)

• Mixed dyslipidemia (combined high LDL-C and triglycerides)

• Prevention of cardiovascular events in high-risk patients

• As an adjunct to diet, exercise, and lifestyle changes for lipid management

Dosage and Administration

• Adults: Typically, 2 mg once daily, taken orally at the same time each day, with or without food.

• Dosage may be adjusted by the physician based on lipid profile response and tolerance.

• Routine blood lipid monitoring is recommended during treatment to assess effectiveness.

• Maintain dietary and lifestyle measures while on therapy for optimal results.

Precautions and Warnings

• Not recommended in patients with active liver disease or unexplained persistent elevations of liver enzymes.

• Use caution in patients with renal impairment.

• Pregnancy and breastfeeding women should avoid use, as safety has not been established.

• Avoid excessive alcohol consumption while on therapy.

• Inform the physician of all medications and supplements, as Pitavastatin may interact with certain drugs.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Pavigard Tablet is generally well-tolerated. Common side effects may include:

• Headache

• Muscle pain or weakness (myalgia)

• Nausea or gastrointestinal discomfort

• Rare: elevated liver enzymes, rhabdomyolysis (severe muscle breakdown), or allergic reactions

Patients should report persistent muscle pain or weakness, dark urine, or jaundice immediately.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Pavigard Tablet 2 mg is an effective statin that lowers LDL cholesterol, improves lipid profiles, and reduces cardiovascular risk, making it an essential therapy for patients with hyperlipidemia or at high risk for heart disease.