Vistarin Injection 2000 Anti-Xa IU/0.2 ml contains Enoxaparin Sodium, a low molecular weight heparin (LMWH) used to prevent and treat blood clots. It works as an anticoagulant, selectively inhibiting Factor Xa and to a lesser degree Factor IIa (thrombin), thereby reducing the formation and extension of thrombi.

This lower-dose pre-filled syringe is ideal for patients requiring prophylactic anticoagulation, including those at moderate risk of deep vein thrombosis (DVT) or pulmonary embolism (PE), such as post-surgical or immobilized patients. Its pre-measured format ensures accurate dosing and convenience for safe therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Vistarin Injection 2000 Anti-Xa IU/0.2 ml is indicated for:

• Prevention of venous thromboembolism (VTE) in patients undergoing surgery or at moderate risk of clot formation
• Prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE)
• Patients requiring short-term anticoagulation in medical or surgical settings
• Adjunct therapy in acute coronary syndromes (ACS) when low-dose anticoagulation is indicated

Mechanism of Action

Enoxaparin Sodium functions by:

• Binding to antithrombin III, enhancing its inhibition of Factor Xa and partially Factor IIa (thrombin)
• Preventing clot formation and propagation in veins and arteries
• Offering predictable anticoagulant activity with a lower risk of heparin-induced thrombocytopenia (HIT) than standard heparin
• Reducing the risk of venous and arterial thromboembolic events in at-risk patients

Dosage and Administration

• Administered via subcutaneous injection, usually in the abdomen
• Pre-filled syringe ensures accurate dosing of 2000 Anti-Xa IU/0.2 ml
• Dosage frequency and duration are determined by clinical indication and patient risk factors
• Avoid intramuscular injections to minimize hematoma formation
• Rotate injection sites to reduce skin irritation
• Monitor platelet count, renal function, and bleeding signs during therapy

Benefits

• Prevents venous thromboembolism and pulmonary embolism in at-risk patients
• Provides predictable anticoagulation with minimal laboratory monitoring
• Lower risk of heparin-induced thrombocytopenia (HIT) compared to standard heparin
• Pre-filled syringe ensures safe, convenient, and accurate administration
• Ideal for prophylactic use in surgical or immobilized patients

Side Effects

Common side effects may include:

• Mild injection site reactions (pain, redness, swelling)
• Minor bruising or bleeding

Rare but serious side effects:

• Severe internal or gastrointestinal bleeding
• Heparin-induced thrombocytopenia (HIT)
• Allergic reactions such as rash, swelling, or difficulty breathing

Seek immediate medical attention if severe bleeding or allergic reactions occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with active bleeding, severe renal or liver impairment, or low platelet count
• Avoid concomitant use with other anticoagulants or antiplatelet drugs unless prescribed
• Pregnancy and breastfeeding: only use under strict medical supervision
• Regular monitoring of blood counts and coagulation parameters is recommended
• Contraindicated in patients with a history of heparin-induced thrombocytopenia (HIT)

Storage

• Store at 2°C to 8°C (refrigerated)
• Protect from light and freezing
• Keep the syringe in its original packaging until use
• Keep out of reach of children
• Do not use after the expiration date.