Vaptan Tablet 15 mg contains Tolvaptan, a selective vasopressin V2-receptor antagonist used to manage conditions associated with abnormal water retention in the body. It works by increasing free water excretion without significant loss of electrolytes, helping to correct low sodium levels and reduce fluid overload in specific clinical conditions.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Composition
Each tablet contains:
Indications
Vaptan Tablet is indicated for:
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Hyponatremia (low blood sodium levels) associated with SIADH
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Fluid overload conditions in heart failure (as prescribed)
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Autosomal dominant polycystic kidney disease (ADPKD)
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Conditions involving excess antidiuretic hormone (ADH) activity
Mechanism of Action
Tolvaptan selectively blocks vasopressin V2 receptors in the kidney collecting ducts. This prevents the action of antidiuretic hormone (ADH), leading to increased excretion of free water (aquaresis) without significant loss of sodium or potassium. This helps correct dilutional hyponatremia and reduce fluid retention.
Dosage & Administration
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Dosage should be strictly determined by a physician
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Usually started under hospital or close medical supervision
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Taken once daily or as prescribed
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Can be taken with or without food
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Fluid intake may be adjusted based on clinical condition
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Regular monitoring of sodium and liver function is required
Precautions
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Must be used under strict medical supervision
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Risk of rapid correction of sodium levels if not monitored properly
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Liver function monitoring is essential during therapy
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Not recommended in patients unable to sense or respond to thirst
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Avoid use during pregnancy unless clearly necessary
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Use cautiously in kidney or liver impairment
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Side Effects
Possible side effects include:
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Increased thirst
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Frequent urination
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Dry mouth
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Dehydration
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Dizziness
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Elevated liver enzymes (rare but serious)
Seek immediate medical attention if confusion, severe weakness, or signs of liver injury occur.
Storage
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Store below 30°C in a dry place
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Protect from light and moisture
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Keep out of reach of children
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Use only under prescription.