Tynifer Capsule contains Ferric Maltol, an oral iron preparation used to treat iron deficiency in adults. It is formulated to deliver iron efficiently through the gastrointestinal tract, helping restore depleted iron stores while maintaining good tolerability.

Indications

• Treatment of iron deficiency in adults

Pharmacology

Ferric Maltol delivers iron in a stable complex that allows uptake across the intestinal wall and transfer to iron-binding proteins such as transferrin and ferritin. Clinical studies have shown that ferric maltol increases key serum iron parameters, including ferritin levels and transferrin saturation (TSAT), thereby correcting iron deficiency.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• Route of administration: Oral

• Recommended dose: 30 mg twice daily

• Administration instructions:

  • Take preferably on an empty stomach, at least 1 hour before or 2 hours after meals

  • Do not open, break, or chew the capsule

• Duration of treatment:

  • Depends on the severity of iron deficiency

  • Generally, a minimum of 12 weeks is required

  • Continue treatment until ferritin levels return to the normal range

• Pediatric use:

  • Safety and effectiveness have not been established in pediatric patients

Drug Interactions

• Concomitant use with dimercaprol may increase the risk of nephrotoxicity; avoid combined use

• May reduce the bioavailability of certain drugs, including:

  • Mycophenolate

  • Ethynyl estradiol

  • Ciprofloxacin

  • Doxycycline

• For drugs where reduced absorption may affect safety or efficacy, administer Tynifer at least 4 hours apart

• Food reduces the bioavailability of iron when taken with Tynifer

Contraindications

• Known hypersensitivity to ferric maltol or any component of the formulation

• History of hemochromatosis or other iron overload syndromes

• Patients receiving repeated blood transfusions

Side Effects

Commonly reported side effects include:

• Flatulence

• Diarrhea

• Constipation

• Discoloration of feces

• Abdominal pain

• Nausea and vomiting

Pregnancy and Lactation

Ferric maltol is not absorbed systemically as an intact complex after oral administration.

• Pregnancy: Maternal use is not expected to result in fetal exposure

• Lactation: Breastfeeding is not expected to expose the infant to ferric maltol
  There are no data on its presence in human milk or effects on milk production.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Avoid use in patients with an active inflammatory bowel disease flare due to potential gastrointestinal inflammation

• Do not administer to patients with iron overload or those receiving intravenous iron

• Assess iron parameters before starting treatment and monitor during therapy

• Accidental overdose of iron-containing products can be fatal in children under 6 years of age

• In case of accidental overdose, seek immediate medical attention

Overdose Effects

No specific data are available on overdose with Tynifer. Early symptoms may include nausea, vomiting, abdominal pain, and diarrhea. Severe cases may lead to hypoperfusion, metabolic acidosis, systemic toxicity, and iron accumulation in storage sites, potentially resulting in hemosiderosis.

Therapeutic Class

• Oral iron preparations

Storage Conditions

• Store in a cool and dry place below 25°C

• Protect from light

• Keep out of reach of children.