Tivion Tablet 2.5 mg contains Tibolone, a synthetic steroid with estrogenic, progestogenic, and androgenic properties. It is primarily prescribed for postmenopausal women to manage symptoms associated with menopause, such as hot flashes, mood swings, and vaginal dryness. Tibolone also helps maintain bone density, reducing the risk of osteoporosis in postmenopausal women.

Tivion provides a convenient once-daily oral therapy that mimics the hormonal activity of natural sex hormones, helping women achieve relief from menopausal symptoms while supporting bone and overall health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tivion Tablet is indicated for:

• Relief of vasomotor symptoms (hot flashes, night sweats) associated with menopause
• Treatment of vaginal atrophy, including dryness and discomfort
• Prevention of postmenopausal osteoporosis in women at risk of bone loss
• Management of mood disturbances and low libido associated with menopause

Mechanism of Action

Tibolone exerts its effects through its metabolites, which have selective tissue-specific actions:

• Estrogenic activity: Reduces hot flashes, improves vaginal health, and maintains bone density.
• Progestogenic activity: Protects the endometrium in women with a uterus.
• Androgenic activity: Enhances libido, mood, and energy levels.

These combined effects provide comprehensive management of menopausal symptoms while minimizing risks associated with traditional hormone replacement therapy.

Dosage and Administration

• Recommended dose: 1 tablet (2.5 mg) once daily.
• Should be taken orally, preferably at the same time each day.
• Can be taken with or without food.
• Do not exceed the recommended dose.
• Use under the guidance of a healthcare professional, especially in women with a history of breast or endometrial cancer.

Benefits

• Relief from hot flashes, night sweats, and mood swings
• Improves vaginal health, reducing dryness and irritation
• Supports bone strength and helps prevent osteoporosis
• Enhances libido and overall well-being
• Convenient once-daily oral therapy

Side Effects

Common side effects may include:

• Headache
• Nausea or mild gastrointestinal discomfort
• Breast tenderness or swelling
• Vaginal bleeding or spotting
• Mood changes or irritability

Serious side effects (rare):

• Increased risk of thromboembolic events (blood clots)
• Stroke or myocardial infarction in women with risk factors
• Endometrial hyperplasia or cancer (if used without progestogenic protection in women with a uterus)

Consult a physician immediately if severe side effects, unusual bleeding, or cardiovascular symptoms occur.

Precautions and Warnings

• Contraindicated in women with a history of breast cancer, endometrial cancer, liver disease, or thromboembolic disorders.
• Use cautiously in patients with cardiovascular risk factors or uncontrolled hypertension.
• Pregnancy and breastfeeding: not recommended.
• Regular monitoring of breast and gynecological health is advised during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Tibolone may interact with:

• Medications affecting liver enzymes (CYP3A4), which can alter tibolone levels
• Hormonal contraceptives or other hormone replacement therapies
• Anticoagulants (monitor for changes in bleeding risk)

Always inform your healthcare provider about all medications and supplements being taken.

Storage

• Store below 25°C in a dry, cool place
• Protect from light and moisture
• Keep out of reach of children
• Do not use after the expiration date.