Dicephin Injection 500 mg/vial IV contains Ceftriaxone Sodium, a third-generation cephalosporin antibiotic widely prescribed for the treatment of moderate to severe bacterial infections. It is administered via intravenous (IV) or intramuscular (IM) injection under the supervision of a qualified healthcare professional. Ceftriaxone is known for its broad-spectrum antibacterial coverage, high efficacy, and convenient dosing schedule due to its long half-life.

Ceftriaxone exerts its bactericidal effect by inhibiting bacterial cell wall synthesis. It binds to specific penicillin-binding proteins (PBPs), preventing the formation of a stable cell wall and leading to the destruction of susceptible bacteria. It is effective against a wide range of Gram-positive and Gram-negative organisms, making it a reliable choice in both hospital and outpatient settings.

The 500 mg strength is suitable for mild to moderate infections and is commonly used in adults and pediatric patients according to clinical judgment and body weight considerations.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dicephin Injection 500 mg/vial is indicated for the treatment of infections caused by susceptible bacteria, including:

• Respiratory tract infections such as pneumonia and bronchitis

• Urinary tract infections (UTIs)

• Ear, nose, and throat infections

• Skin and soft tissue infections

• Bone and joint infections

• Intra-abdominal infections

• Septicemia (bloodstream infections)

• Meningitis

• Uncomplicated and complicated gonorrhea

It is also used as surgical prophylaxis to reduce the risk of postoperative infections in selected procedures.

Dosage and Administration

The dosage of Dicephin depends on the severity and type of infection, as well as patient age, body weight, and renal or hepatic function.

• Adults: Usually 500 mg to 1 gm once daily or divided into two doses. Severe infections may require higher doses as prescribed.

• Children: Dosage is calculated according to body weight.

• Neonates: Special dosing adjustments are required.

The vial should be reconstituted with a recommended diluent before administration. It must be administered by trained healthcare personnel. The duration of therapy depends on the clinical response and nature of the infection.

Precautions

• Contraindicated in patients with known hypersensitivity to ceftriaxone or other cephalosporins.

• Use cautiously in patients allergic to penicillins or other beta-lactam antibiotics.

• Monitor renal and hepatic function during prolonged therapy.

• Avoid use with calcium-containing IV solutions in neonates.

• Prolonged use may lead to superinfection with non-susceptible organisms.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Dicephin Injection is generally well tolerated. Possible side effects include:

• Pain, redness, or swelling at the injection site

• Diarrhea

• Nausea or vomiting

• Skin rash or itching

• Changes in liver enzyme levels

Serious allergic reactions are rare but require immediate medical attention.

Storage

Store below 25°C in a dry place, protected from light. Keep out of reach of children. Use reconstituted solution within the recommended time period.

Dicephin Injection 500 mg/vial provides dependable and effective antibacterial therapy when prescribed appropriately by a healthcare professional.