Tenobis Plus Tablet 2.5 mg+6.25 mg is a fixed-dose combination medicine containing Bisoprolol Fumarate 2.5 mg and Hydrochlorothiazide 6.25 mg. It is indicated for the effective management of hypertension (high blood pressure) in patients who require combination therapy for better blood pressure control.

This dual-action formula combines a cardioselective beta-blocker with a thiazide diuretic to provide complementary mechanisms for lowering blood pressure. By reducing both heart workload and excess fluid retention, Tenobis Plus helps maintain stable blood pressure levels and lowers the risk of serious cardiovascular complications such as heart attack and stroke.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Bisoprolol Fumarate 2.5 mg

• Hydrochlorothiazide 6.25 mg

Mechanism of Action

Bisoprolol is a selective beta-1 adrenergic receptor blocker that acts primarily on the heart. It reduces heart rate, decreases cardiac output, and lowers blood pressure by limiting the effects of stress hormones like adrenaline.

Hydrochlorothiazide is a thiazide diuretic that works by increasing the excretion of sodium and water through the kidneys. This reduces blood volume and decreases vascular resistance, further contributing to blood pressure reduction.

The combination provides enhanced antihypertensive effects compared to either medicine alone.

Indications

Tenobis Plus Tablet is indicated for:

• Treatment of essential hypertension

• Patients not adequately controlled with single-agent therapy

• Long-term management of elevated blood pressure

It may be prescribed as initial combination therapy or after titration of individual components.

Dosage and Administration

• The usual dose is one tablet once daily or as directed by a physician.

• It is generally taken in the morning to avoid nighttime urination due to the diuretic component.

• Swallow the tablet whole with water.

• It may be taken with or without food.

Do not stop the medication abruptly without consulting a healthcare professional.

Benefits

• Dual mechanism for effective blood pressure control

• Reduces heart workload and fluid retention

• Helps prevent cardiovascular complications

• Convenient once-daily dosing

• Improves patient adherence with combination therapy

Precautions

• Monitor blood pressure, heart rate, and electrolyte levels regularly.

• Use cautiously in patients with asthma, diabetes, gout, or kidney impairment.

• Hydrochlorothiazide may cause electrolyte imbalance such as low potassium levels.

• Avoid use in severe bradycardia or advanced heart block without medical supervision.

• Not recommended during pregnancy unless clearly advised by a physician.

Adequate hydration and regular follow-up are important during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Dizziness

• Fatigue

• Slow heart rate

• Increased urination

• Electrolyte imbalance

• Mild gastrointestinal discomfort

Most side effects are mild and manageable. Seek medical attention if severe weakness, irregular heartbeat, or allergic reactions occur.

Storage

• Store below 30°C

• Keep in a dry place away from moisture

• Protect from direct sunlight

• Keep out of reach of children

Tenobis Plus Tablet 2.5 mg+6.25 mg provides a balanced and effective combination therapy for patients requiring comprehensive blood pressure management under proper medical supervision.