Synroid Tablet 50 mcg contains Levothyroxine Sodium, a synthetic form of the thyroid hormone thyroxine (T4). It is primarily used to replace or supplement the thyroid hormone in patients with hypothyroidism, a condition in which the thyroid gland does not produce enough hormone.

Levothyroxine Sodium restores normal thyroid hormone levels in the body, helping regulate metabolism, energy production, and overall growth and development. Synroid Tablet 50 mcg is a well-tolerated and effective therapy for maintaining thyroid hormone balance and preventing the complications associated with thyroid hormone deficiency.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Thyroid Hormone Replacement Therapy

Indications

Synroid Tablet 50 mcg is indicated for:

• Primary hypothyroidism (underactive thyroid)

• Secondary or tertiary hypothyroidism (pituitary or hypothalamic origin)

• Goiter (enlarged thyroid gland) to reduce thyroid volume and suppress growth

• Myxedema (severe hypothyroidism)

• Management of thyroid hormone deficiency following thyroidectomy or radioactive iodine therapy

• Treatment of congenital hypothyroidism to ensure normal growth and development in children

It is also used as a part of therapy to manage certain types of thyroid cancer and for diagnostic suppression testing in thyroid disorders.

Pharmacology

Levothyroxine Sodium is a synthetic T4 hormone that mimics the action of natural thyroxine produced by the thyroid gland. Once absorbed in the gastrointestinal tract, it is converted to the active form, triiodothyronine (T3), in peripheral tissues.

Levothyroxine binds to thyroid hormone receptors in the nucleus of target cells, stimulating gene expression and protein synthesis. This leads to:

• Increased basal metabolic rate

• Enhanced oxygen consumption

• Improved energy production

• Regulation of growth and development in children

• Stabilization of cholesterol and lipid metabolism

The therapeutic effect of Synroid Tablet 50 mcg restores normal physiological function in patients with thyroid hormone deficiency.

Dosage and Administration

The dosage of Synroid Tablet 50 mcg must be individualized according to patient age, weight, clinical condition, and severity of hypothyroidism.

• Typically taken once daily, preferably in the morning on an empty stomach, 30–60 minutes before breakfast

• Swallow the tablet whole with water; do not crush or chew

• Regular monitoring of thyroid function tests (T3, T4, TSH) is necessary to adjust dosage

• Consistency in brand or formulation is recommended to maintain stable hormone levels

Special populations, such as elderly patients or those with cardiac disease, may require lower initial doses to reduce the risk of adverse cardiovascular events.

Precautions

• Use cautiously in patients with cardiovascular disorders, including angina, arrhythmias, or recent myocardial infarction

• Monitor thyroid function regularly to avoid over- or under-treatment

• Inform the physician of other medications, as certain drugs may interfere with levothyroxine absorption (e.g., calcium, iron, antacids)

• Pregnancy and lactation require close monitoring and dose adjustment as needed

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Synroid Tablet 50 mcg is generally well tolerated, but excessive dosing or sensitivity may lead to:

• Palpitations or rapid heartbeat

• Nervousness or anxiety

• Insomnia

• Weight loss

• Tremors

• Sweating and heat intolerance

• Rare allergic reactions

Seek medical attention if severe symptoms such as chest pain, shortness of breath, or irregular heartbeat occur.

Storage

Store below 25°C in a dry, dark place. Keep the tablets in their original packaging to protect from light and moisture. Keep out of reach of children.