Seraflo Inhaler combines Salmeterol 25 mcg and Fluticasone Propionate 250 mcg per puff, providing a dual-action therapy for the management of asthma and chronic obstructive pulmonary disease (COPD). This inhaler integrates a long-acting bronchodilator with an anti-inflammatory corticosteroid, offering both symptom relief and long-term disease control.

Salmeterol is a long-acting β2-adrenergic receptor agonist (LABA) that helps relax airway muscles, making breathing easier, while Fluticasone Propionate is an inhaled corticosteroid (ICS) that reduces airway inflammation, swelling, and mucus production. Together, they improve lung function, reduce asthma exacerbations, and enhance quality of life for patients with chronic respiratory conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Salmeterol 25 mcg per puff

• Fluticasone Propionate 250 mcg per puff

Mechanism of Action

Dual mechanism ensures comprehensive asthma and COPD management:

1. Salmeterol:

   • Stimulates β2-adrenergic receptors in bronchial smooth muscle

   • Causes relaxation of airway muscles (bronchodilation)

   • Provides long-lasting relief from bronchospasm, wheezing, and shortness of breath

2. Fluticasone Propionate:

   • Reduces airway inflammation and edema

   • Inhibits release of inflammatory mediators

   • Prevents airway remodeling and reduces frequency of asthma attacks

The combination ensures both immediate bronchodilation and long-term anti-inflammatory protection, essential for effective control of chronic respiratory conditions.

Indications

Seraflo Inhaler (25 mcg+250 mcg) is indicated for:

• Maintenance treatment of asthma in adults and adolescents not adequately controlled with inhaled corticosteroids alone

• Prevention of asthma symptoms and reduction of exacerbations

• Long-term management of chronic obstructive pulmonary disease (COPD) with persistent symptoms

• Patients requiring both anti-inflammatory therapy and bronchodilation

It is not intended for the relief of acute asthma attacks; a short-acting bronchodilator should be used for immediate symptom relief.

Dosage and Administration

• The typical dosage is one inhalation twice daily (morning and evening) or as prescribed by a healthcare professional.

• Shake the inhaler well before each use.

• Exhale fully before placing the mouthpiece in the mouth and inhaling deeply while pressing the canister.

• Hold the breath for 10 seconds after inhalation, then exhale slowly.

• Rinse the mouth with water after each use to reduce the risk of oral thrush.

Consistency in administration is critical for optimal symptom control and prevention of exacerbations.

Benefits

• Reduces airway inflammation and bronchospasm

• Improves breathing and exercise tolerance

• Decreases frequency and severity of asthma attacks

• Long-acting bronchodilation with anti-inflammatory protection

• Convenient inhaler for easy, targeted lung delivery

Precautions

• Not for acute asthma attacks or sudden breathing difficulty

• Use with caution in patients with cardiovascular disorders, diabetes, or hyperthyroidism

• Regular monitoring may be required for systemic corticosteroid side effects

• Pregnant or breastfeeding women should consult a physician before use

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Oral thrush (candidiasis)

• Hoarseness or throat irritation

• Mild tremors or palpitations

• Headache or dizziness

Rare but serious side effects:

• Paradoxical bronchospasm

• Severe allergic reactions

• High blood pressure or heart rate irregularities

Storage

Store below 30°C in a dry place, protected from sunlight. Keep the mouthpiece clean and capped when not in use. Keep out of reach of children.

Seraflo Inhaler (25 mcg+250 mcg) provides effective, long-term management of asthma and COPD by combining Salmeterol and Fluticasone Propionate to improve lung function, reduce exacerbations, and enhance patient quality of life.