Seraflo Inhalation Capsule 50 mcg+100 mcg is a combination therapy containing Salmeterol, a long-acting bronchodilator, and Fluticasone Propionate, an inhaled corticosteroid. It is designed for maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD), providing both bronchodilation and anti-inflammatory effects in a convenient inhalation capsule form for use with a dry powder inhaler (DPI).

Salmeterol relaxes the muscles in the airways to ease breathing, while Fluticasone Propionate reduces inflammation, swelling, and mucus buildup in the lungs. Together, they improve lung function, control chronic symptoms, and reduce the risk of exacerbations. Seraflo Inhalation Capsule 50 mcg+100 mcg is particularly useful for patients who require consistent control of respiratory symptoms without relying solely on short-acting bronchodilators.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Salmeterol 50 mcg per inhalation

• Fluticasone Propionate 100 mcg per inhalation

Mechanism of Action

Dual-action mechanism for effective respiratory management:

1. Salmeterol (Long-Acting β2-Adrenergic Agonist):

   • Binds to β2-adrenergic receptors in bronchial smooth muscles

   • Relaxes airway muscles, providing sustained bronchodilation

   • Helps reduce wheezing, shortness of breath, and bronchospasm

2. Fluticasone Propionate (Inhaled Corticosteroid):

   • Reduces airway inflammation and edema

   • Inhibits the release of inflammatory mediators

   • Prevents airway remodeling and reduces the frequency of exacerbations

The combination ensures both immediate relief of bronchospasm and long-term anti-inflammatory protection, making it ideal for chronic respiratory conditions.

Indications

Seraflo Inhalation Capsule 50 mcg+100 mcg is indicated for:

• Maintenance therapy of asthma in adults and adolescents not adequately controlled with inhaled corticosteroids alone

• Long-term management of COPD with persistent respiratory symptoms

• Prevention of asthma exacerbations and improvement of lung function

• Patients requiring both bronchodilator and anti-inflammatory therapy

It is not suitable for acute asthma attacks; a short-acting bronchodilator should be used in emergencies.

Dosage and Administration

• The usual dosage is one inhalation twice daily (morning and evening) via a dry powder inhaler.

• Open the inhaler, insert the capsule, and pierce it according to device instructions.

• Inhale the powder deeply and hold your breath for 10 seconds before exhaling.

• Rinse the mouth with water after each use to reduce the risk of oral thrush.

Consistent administration is essential for optimal asthma and COPD control.

Benefits

• Provides long-lasting bronchodilation and anti-inflammatory action

• Reduces airway inflammation, wheezing, and shortness of breath

• Decreases frequency and severity of asthma and COPD exacerbations

• Convenient capsule formulation for use with a dry powder inhaler

• Enhances quality of life by improving breathing and exercise tolerance

Precautions

• Not intended for acute relief of asthma symptoms

• Use with caution in patients with cardiovascular disorders, high blood pressure, diabetes, or thyroid disorders

• Monitor for systemic corticosteroid effects during long-term use

• Consult a physician before use during pregnancy or breastfeeding

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Oral thrush or sore throat

• Hoarseness or throat irritation

• Mild tremors or palpitations

• Headache or dizziness

Rare but serious side effects:

• Paradoxical bronchospasm

• Severe allergic reactions

• Cardiovascular events such as arrhythmias or hypertension

Storage

Store below 30°C in a cool, dry place, protected from sunlight and moisture. Keep capsules in their blister pack until use and out of reach of children.

Seraflo Inhalation Capsule 50 mcg+100 mcg provides effective maintenance therapy for asthma and COPD, combining Salmeterol and Fluticasone Propionate to improve lung function, prevent exacerbations, and enhance patient comfort.