Prufit Tablet 2 mg contains prucalopride succinate, a selective serotonin (5-HT4) receptor agonist used for the treatment of chronic constipation in adults. It is prescribed when conventional laxatives do not provide adequate relief. This higher-strength dose is used in patients requiring stronger prokinetic action to improve bowel movement frequency.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Prucalopride Succinate 2 mg
• Dosage Form: Oral tablet

Mechanism of Action

Prucalopride selectively stimulates 5-HT4 receptors in the gastrointestinal tract. This enhances colonic peristalsis and accelerates bowel transit. By improving coordinated intestinal contractions, it helps restore normal bowel function and reduces symptoms of chronic constipation such as straining, bloating, and infrequent stools.

Indications

Prufit Tablet 2 mg is indicated for:

• Chronic idiopathic constipation in adults
• Constipation not responding to laxatives
• Functional bowel motility disorders
• Patients requiring stronger prokinetic therapy under medical supervision

Dosage and Administration

• Usually taken once daily as prescribed by a physician
• Can be taken with or without food
• Swallow the tablet whole with water
• Treatment should be continued as advised for consistent results
• Dose may be adjusted based on response and tolerability

Benefits

• Improves bowel movement frequency
• Reduces straining and abdominal discomfort
• Enhances natural colonic motility
• Effective in laxative-resistant constipation
• Simple once-daily dosing for better compliance

Possible Side Effects

Common side effects may include:

• Headache
• Nausea
• Abdominal pain
• Diarrhea

Less common side effects may include:

• Dizziness
• Fatigue
• Mood changes (rare)

Precautions and Warnings

• Use only under medical supervision
• Not recommended in intestinal obstruction or severe inflammatory bowel disease
• Use cautiously in patients with severe kidney or liver impairment
• Dose adjustment may be required in renal impairment
• Inform physician if symptoms persist or worsen

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Prufit Tablet 2 mg (Prucalopride Succinate) is an effective prokinetic medication used for the management of chronic constipation. It helps improve intestinal motility and bowel regularity, especially in patients who do not respond to conventional laxatives, when used under proper medical supervision.