Prufit Tablet 1 mg contains prucalopride succinate, a selective serotonin (5-HT4) receptor agonist used for the treatment of chronic constipation. It works by enhancing colonic motility, helping restore normal bowel movements in patients who do not respond adequately to conventional laxatives.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Prucalopride Succinate 1 mg
• Dosage Form: Oral tablet

Mechanism of Action

Prucalopride selectively stimulates 5-HT4 receptors in the gastrointestinal tract. This enhances peristaltic reflexes and increases colonic motility, leading to improved bowel movement frequency and reduced symptoms of chronic constipation. It acts primarily on the colon with minimal cardiovascular effects due to its high selectivity.

Indications

Prufit Tablet 1 mg is indicated for:

• Chronic idiopathic constipation in adults
• Patients unresponsive to conventional laxatives
• Functional constipation associated with reduced bowel motility

Dosage and Administration

• Usually taken once daily as prescribed by a physician
• Can be taken with or without food
• Swallow the tablet whole with water
• Regular use is recommended for consistent bowel regulation
• Dose adjustment may be required based on response

Benefits

• Improves frequency of bowel movements
• Reduces symptoms of chronic constipation such as straining and bloating
• Enhances colonic motility naturally
• Suitable for patients not responding to standard laxatives
• Once-daily convenient dosing

Possible Side Effects

Common side effects may include:

• Headache
• Nausea
• Abdominal pain
• Diarrhea

Less common side effects may include:

• Dizziness
• Fatigue
• Mood changes (rare)

Precautions and Warnings

• Use only under medical supervision
• Not recommended for use in intestinal obstruction or severe inflammatory bowel disease
• Use cautiously in patients with severe kidney or liver impairment
• Inform doctor if symptoms persist or worsen
• Dose should be adjusted in patients with renal impairment

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Prufit Tablet 1 mg (Prucalopride Succinate) is an effective prokinetic agent used for the management of chronic constipation. It helps improve bowel movement frequency and intestinal motility, offering relief in patients who do not respond to traditional laxatives when used under medical supervision.