Progut Capsule 40 mg contains Esomeprazole, a proton pump inhibitor (PPI) that effectively reduces gastric acid secretion. It is used in the management of acid-related gastrointestinal disorders such as gastroesophageal reflux disease (GERD), peptic ulcer disease, erosive esophagitis, and Zollinger-Ellison syndrome. This higher-strength formulation is suitable for moderate to severe acid-related conditions requiring stronger acid suppression and faster symptom relief.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Esomeprazole 40 mg

Indications

Progut Capsule is indicated for:

• Gastroesophageal reflux disease (GERD)
• Erosive esophagitis
• Gastric and duodenal ulcers
• Zollinger-Ellison syndrome
• Dyspepsia due to excess acid secretion
• Prevention of NSAID-induced gastric ulcers (as prescribed)

Mechanism of Action

Esomeprazole is the S-isomer of omeprazole and works by selectively and irreversibly inhibiting the hydrogen-potassium ATPase enzyme (proton pump) in gastric parietal cells. This blocks the final step of acid production, resulting in a significant and sustained reduction in gastric acid secretion, allowing healing of damaged gastrointestinal tissues.

Dosage and Administration

• Usually taken once daily before meals, preferably in the morning.
• Swallow the capsule whole with water; do not crush or chew.
• Dosage and duration depend on severity of condition and physician’s advice.
• Use the lowest effective dose for the shortest duration necessary.

Benefits

• Strong and long-lasting acid suppression
• Effective relief from heartburn and acid reflux
• Promotes healing of gastric and duodenal ulcers
• Helps prevent recurrence of acid-related disorders
• Improves digestive comfort and quality of life

Side Effects

Progut Capsule is generally well tolerated. Possible side effects include:

• Headache
• Nausea or vomiting
• Abdominal pain
• Diarrhea or constipation
• Flatulence

Long-term use may rarely lead to vitamin B12 or magnesium deficiency.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with liver impairment.
• Long-term therapy should be medically supervised.
• May interact with medications such as clopidogrel and antifungals.
• Not recommended during pregnancy or breastfeeding unless prescribed.
• Rule out gastric malignancy before prolonged use in ulcer patients.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.