Probis Plus Tablet is a combination medication designed to manage high blood pressure (hypertension) effectively. It contains Bisoprolol Fumarate 2.5 mg, a beta-blocker, and Hydrochlorothiazide 6.25 mg, a thiazide diuretic. By combining these two agents, Probis Plus targets different mechanisms in the body to help lower blood pressure, reduce strain on the heart, and improve overall cardiovascular health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

• Bisoprolol Fumarate selectively blocks beta-1 adrenergic receptors in the heart. This slows the heart rate and decreases the force of heart contractions, reducing cardiac workload and lowering blood pressure.
• Hydrochlorothiazide is a thiazide diuretic that promotes the elimination of excess salt and water from the body through urine. This reduces blood volume and further decreases blood pressure.

Together, these two components provide complementary effects that improve blood pressure control while potentially minimizing side effects associated with higher doses of a single drug.

Indications

Probis Plus Tablet is indicated for:

• Primary hypertension (high blood pressure)
• Patients who require combination therapy for better blood pressure control
• Reducing the risk of cardiovascular events in patients with coexisting conditions such as diabetes or heart disease

Dosage and Administration

• The standard dose is one tablet once daily, or as prescribed by a healthcare professional.
• Can be taken with or without food.
• Should be taken at the same time each day to maintain consistent blood pressure control.
• Regular monitoring of blood pressure, kidney function, and electrolyte levels is recommended during treatment.

Benefits

• Provides dual-action blood pressure control through heart rate reduction and diuresis
• May improve cardiovascular outcomes by reducing cardiac workload and fluid overload
• Convenient once-daily dosing increases adherence
• Combines two effective antihypertensive agents in a single tablet

Precautions

• Not suitable for patients with severe bradycardia, hypotension, or kidney failure.
• Use with caution in patients with diabetes, gout, or electrolyte imbalances.
• Inform your doctor about other medications to prevent drug interactions.
• Do not stop therapy abruptly without medical advice, as this may worsen heart conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Possible side effects include:

• Dizziness or fatigue
• Headache
• Mild swelling of ankles or feet
• Increased urination due to diuretic action

Seek immediate medical attention if severe side effects occur, such as very low blood pressure, slow heart rate, or severe allergic reactions.

Storage

• Store in a cool, dry place, away from sunlight and moisture.
• Keep out of reach of children.

Probis Plus Tablet offers a reliable, effective approach to managing hypertension, combining the benefits of beta-blocker therapy with diuretic action to support heart health and long-term blood pressure control.