Preclot AS Tablet is a combination of Clopidogrel and Aspirin, two antiplatelet agents that work together to prevent the formation of harmful blood clots. It is widely used in patients at high risk of cardiovascular events such as heart attack and stroke. This dual therapy provides enhanced protection by targeting different pathways of platelet aggregation.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Composition
-
Clopidogrel 75 mg
-
Aspirin 75 mg
Indications
Preclot AS Tablet is indicated for:
-
Prevention of myocardial infarction (heart attack)
-
Prevention of ischemic stroke
-
Acute coronary syndrome (ACS)
-
Post-stent implantation (to prevent stent thrombosis)
-
Peripheral arterial disease (PAD)
-
Secondary prevention of cardiovascular events in high-risk patients
Mechanism of Action
-
Clopidogrel inhibits the P2Y12 ADP receptor on platelets, preventing platelet activation and aggregation.
-
Aspirin irreversibly inhibits cyclooxygenase-1 (COX-1), reducing thromboxane A2 formation, a key mediator of platelet aggregation.
Together, they provide dual antiplatelet therapy (DAPT), significantly reducing the risk of arterial clot formation.
Dosage and Administration
-
Usually taken once daily or as directed by a physician.
-
Swallow whole with water; can be taken with or without food.
-
Do not discontinue without medical advice, especially after stent placement.
-
Dosage duration depends on patient condition and physician recommendation.
Benefits
-
Strong protection against heart attack and stroke
-
Dual mechanism reduces platelet aggregation effectively
-
Essential in post-stent and high-risk cardiac patients
-
Improves blood flow in narrowed arteries
-
Reduces risk of recurrent cardiovascular events
Side Effects
Preclot AS Tablet may cause:
-
Increased risk of bleeding
-
Bruising easily
-
Gastric irritation or stomach pain
-
Nausea
-
Nosebleeds
Serious bleeding (gastrointestinal or intracranial) requires immediate medical attention.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Precautions and Warnings
-
Use with caution in patients with bleeding disorders or ulcers.
-
Avoid use before surgery or dental procedures unless advised.
-
Do not combine with other anticoagulants unless prescribed.
-
Avoid alcohol to reduce gastric bleeding risk.
-
Not recommended in active bleeding conditions.
Storage
-
Store below 30°C
-
Protect from moisture and light
-
Keep out of reach of children.