Pegalin ER Tablet 330 mg contains Pregabalin in an extended-release formulation designed to provide sustained and stable therapeutic action throughout the day. It is used for the management of neuropathic pain, epilepsy, and generalized anxiety disorder. This high-strength, once-daily formulation ensures continuous symptom control with improved patient compliance and reduced dosing frequency.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pregabalin 330 mg (Extended Release)

Indications

Pegalin ER Tablet is indicated for:

• Neuropathic pain (diabetic neuropathy, post-herpetic neuralgia)
• Fibromyalgia
• Adjunct therapy for partial seizures (epilepsy)
• Generalized anxiety disorder (GAD)
• Chronic nerve pain requiring long-term sustained therapy

Mechanism of Action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P, leading to decreased neuronal excitability. The extended-release formulation allows gradual absorption, maintaining consistent plasma levels and providing prolonged symptom relief over 24 hours.

Dosage and Administration

• Typically taken once daily or as directed by a physician.
• Swallow whole with water; do not crush, chew, or break the tablet.
• Take at the same time each day for optimal effect.
• Dosage is individualized based on patient condition and response.
• Do not discontinue abruptly without medical supervision.

Benefits

• Strong, long-lasting relief from neuropathic pain
• Once-daily dosing improves convenience and adherence
• Stable drug levels throughout the day
• Reduces burning, tingling, and shooting nerve pain
• Helps manage anxiety symptoms effectively
• Supports seizure control in epilepsy patients

Side Effects

Pegalin ER Tablet may cause:

• Drowsiness or dizziness
• Blurred vision
• Fatigue
• Weight gain
• Dry mouth
• Peripheral edema (rare)

Most side effects are mild and improve with continued use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• May cause dizziness; avoid driving or operating machinery.
• Use with caution in patients with kidney impairment (dose adjustment required).
• Do not crush or split the tablet due to extended-release formulation.
• Avoid alcohol during treatment.
• Do not stop abruptly; gradual tapering is necessary.
• Use only under medical supervision.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.