Pegalin Capsule 150 mg contains Pregabalin, a centrally acting neuromodulator used for the management of neuropathic pain, epilepsy, and generalized anxiety disorder. It works by reducing abnormal nerve activity in the brain and spinal cord, helping to relieve nerve pain, control seizures, and improve anxiety-related symptoms. This higher-strength dosage is typically used in patients requiring stronger therapeutic control of moderate to severe neuropathic conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pregabalin 150 mg

Indications

Pegalin Capsule is indicated for:

• Neuropathic pain (diabetic neuropathy, post-herpetic neuralgia)
• Fibromyalgia
• Adjunct therapy for partial seizures (epilepsy)
• Generalized anxiety disorder (GAD)
• Neuropathic pain due to spinal cord injury

Mechanism of Action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P, resulting in decreased neuronal excitability and effective relief of neuropathic pain, anxiety, and seizure activity.

Dosage and Administration

• Dosage is individualized based on the patient’s condition and clinical response.
• Usually administered 1–2 times daily or as directed by a physician.
• Swallow whole with water, with or without food.
• Do not discontinue suddenly; gradual tapering is required under medical supervision.

Benefits

• Strong relief from moderate to severe neuropathic pain
• Reduces burning, tingling, and shooting nerve sensations
• Helps control generalized anxiety disorder
• Improves sleep quality in chronic pain patients
• Supports adjunct therapy in epilepsy management

Side Effects

Pegalin Capsule may cause:

• Drowsiness or dizziness
• Blurred vision
• Weight gain
• Dry mouth
• Difficulty concentrating
• Peripheral edema (rare)

Most side effects are mild and often improve with continued use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• May cause dizziness; avoid driving or operating machinery.
• Use with caution in patients with renal impairment (dose adjustment required).
• Do not stop abruptly; tapering is necessary under medical supervision.
• Avoid alcohol during treatment.
• Use only under physician supervision.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.