Parib Tablet 150 mg contains Olaparib, a targeted anticancer medication classified as a poly (ADP-ribose) polymerase (PARP) inhibitor. It is specifically designed to treat certain types of cancers associated with inherited or acquired BRCA gene mutations. By interfering with the cancer cell’s ability to repair damaged DNA, Parib helps slow tumor growth and supports improved disease control.

Olaparib works by inhibiting the PARP enzyme, which plays a crucial role in repairing single-strand DNA breaks. In patients with BRCA1 or BRCA2 mutations, cancer cells already have impaired DNA repair mechanisms. Blocking PARP activity leads to accumulation of DNA damage, ultimately resulting in cancer cell death while minimizing impact on normal healthy cells. This targeted mechanism makes Parib Tablet 150 mg an important option in precision oncology.

Parib Tablet 150 mg is administered orally and is commonly prescribed by oncologists as maintenance therapy or active treatment depending on the type and stage of cancer.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Parib Tablet 150 mg is indicated for the treatment of:

• Advanced ovarian cancer

• HER2-negative metastatic breast cancer with BRCA mutation

• Metastatic pancreatic cancer with BRCA mutation

• Prostate cancer associated with homologous recombination repair (HRR) gene mutations

Treatment eligibility is determined based on genetic testing and clinical evaluation. It may be used as monotherapy or as maintenance therapy following response to platinum-based chemotherapy.

Dosage and Administration

• The recommended dosage is typically 300 mg twice daily (two 150 mg tablets per dose), or as directed by an oncologist.

• Tablets should be swallowed whole with water.

• Can be taken with or without food.

• Doses should be taken approximately 12 hours apart.

Dose adjustments may be required based on tolerability, kidney function, or side effects. Patients should strictly follow their physician’s instructions and not alter the dose without medical advice.

Benefits of Parib Tablet 150 mg

• Targeted therapy for BRCA-mutated cancers

• Helps delay disease progression

• Oral administration for convenient at-home treatment

• Reduces reliance on continuous intravenous chemotherapy

• Clinically proven efficacy in multiple cancer types

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Fatigue or weakness

• Nausea and vomiting

• Anemia

• Decreased appetite

• Diarrhea

• Headache

Regular monitoring of blood counts is necessary during treatment. Serious but rare side effects may include bone marrow suppression or lung inflammation. Any unusual symptoms such as persistent cough, shortness of breath, or severe fatigue should be reported immediately.

Precautions

• Not recommended during pregnancy or breastfeeding due to potential fetal harm.

• Effective contraception is advised during treatment and for a period after completion.

• Use with caution in patients with kidney or liver impairment.

• Inform the physician about all concurrent medications to avoid interactions, especially strong CYP3A inhibitors or inducers.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Parib Tablet 150 mg provides a scientifically advanced and targeted treatment approach for eligible patients, offering improved control of BRCA-related cancers under specialized medical supervision.