Palotic Injection 0.25 mg/5 ml contains Palonosetron, a second-generation selective serotonin (5-HT3) receptor antagonist used for the prevention and treatment of nausea and vomiting. It is especially effective in chemotherapy-induced nausea and vomiting (CINV) and post-operative nausea and vomiting (PONV). Its long half-life ensures prolonged antiemetic protection with a single administration.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Palonosetron 0.25 mg per 5 ml solution

Indications

Palotic Injection is indicated for:

• Prevention of chemotherapy-induced nausea and vomiting (acute and delayed phases)
• Prevention and management of post-operative nausea and vomiting
• Nausea and vomiting associated with surgical procedures or anesthesia
• Supportive antiemetic therapy in oncology patients

Mechanism of Action

Palonosetron selectively blocks serotonin (5-HT3) receptors in both the central nervous system and gastrointestinal tract. By inhibiting serotonin activity, it prevents stimulation of the vomiting reflex. Its strong receptor binding affinity and long elimination half-life provide sustained protection against nausea and vomiting.

Dosage and Administration

• Administered intravenously as a single dose prior to chemotherapy or surgery, or as directed by a physician.
• Must be given by a healthcare professional in a clinical setting.
• Dosage may vary depending on patient condition and treatment protocol.

Benefits

• Effective prevention of acute and delayed nausea and vomiting
• Long-lasting antiemetic action with single-dose use
• Improves patient comfort during chemotherapy and surgery
• Reduces need for repeated antiemetic therapy
• Well-established safety and efficacy profile

Side Effects

Palotic Injection is generally well tolerated. Possible side effects include:

• Headache
• Constipation
• Dizziness
• Fatigue
• Injection site reactions

Serious adverse effects are rare but should be reported to a healthcare provider if they occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under medical supervision.
• Caution in patients with cardiac arrhythmias or QT prolongation.
• Dose adjustment may be required in hepatic impairment.
• Inform your doctor about all concurrent medications.
• Not intended for self-administration.

Storage

• Store below 25°C
• Protect from light
• Do not freeze
• Keep out of reach of children.