Ostan Plus Tablet 100 mg + 25 mg is a potent combination antihypertensive medication containing Losartan Potassium (100 mg) and Hydrochlorothiazide (25 mg). This high-strength formulation is designed for adults who require stronger blood pressure control, particularly when monotherapy with a single agent is insufficient.

Losartan Potassium is an angiotensin II receptor blocker (ARB) that relaxes blood vessels, improving blood flow and reducing the heart’s workload. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of excess sodium and water through the kidneys, further reducing blood pressure and preventing fluid retention. Together, these two agents provide a complementary mechanism for controlling hypertension effectively.

Ostan Plus 100 mg + 25 mg is ideal for patients with moderate to severe hypertension or those who have not achieved target blood pressure with lower-dose therapy. By combining two antihypertensive agents in a single tablet, it ensures convenient once-daily dosing and improves adherence to treatment, promoting long-term cardiovascular health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Contains Losartan Potassium 100 mg + Hydrochlorothiazide 25 mg per tablet

• Combines ARB and diuretic for enhanced blood pressure control

• Suitable for patients requiring higher-dose therapy

• Reduces the risk of stroke, heart attack, and heart failure

• Helps manage fluid retention and supports kidney function

• Convenient oral tablet with once-daily dosing

Indications

Ostan Plus Tablet 100 mg + 25 mg is primarily indicated for:

• Hypertension: Effective in lowering high blood pressure in adults

• Patients not adequately controlled on lower doses: For those requiring stronger combination therapy

• Fluid retention management: Helps reduce mild edema associated with hypertension

• Cardiovascular risk reduction: Reduces the risk of stroke, heart attack, and heart failure in hypertensive patients

This combination therapy should be used alongside lifestyle interventions, such as a low-sodium diet, regular exercise, and weight management, to optimize blood pressure control.

Mechanism of Action

• Losartan Potassium: Blocks angiotensin II from binding to AT1 receptors in blood vessels, preventing vasoconstriction and lowering blood pressure while reducing strain on the heart and kidneys.

• Hydrochlorothiazide: Promotes renal excretion of sodium and water, decreasing blood volume and further reducing blood pressure.

By acting on both vascular resistance and fluid balance, Ostan Plus provides effective and sustained control of hypertension.

Dosage and Administration

• Typically administered once daily, with or without food

• Swallow tablets whole with water

• The exact dosage should be determined by a healthcare professional based on blood pressure response and patient condition

• Continue therapy as prescribed, even if blood pressure improves early

Possible Side Effects

Ostan Plus Tablet 100 mg + 25 mg is generally well tolerated, but potential side effects may include:

• Dizziness or lightheadedness

• Headache

• Fatigue

• Increased urination

• Mild gastrointestinal discomfort

• Rarely, electrolyte imbalances (low potassium or sodium) or kidney dysfunction

Seek medical attention immediately if severe side effects or allergic reactions occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Not recommended during pregnancy, particularly in the second and third trimesters

• Use with caution in patients with kidney or liver impairment

• Regular monitoring of blood electrolytes, kidney function, and blood pressure may be advised

• Inform your doctor of all other medications, especially diuretics, NSAIDs, or other antihypertensives

Storage Instructions

• Store in a cool, dry place below 30°C

• Keep the tablet container tightly closed

• Protect from moisture and sunlight

• Keep out of reach of children.