Oramet-SR Tablet 1000 mg contains Metformin Hydrochloride, a widely prescribed oral antidiabetic medication used for managing type 2 diabetes mellitus. This is a sustained-release (SR) formulation, designed to release Metformin gradually over time, providing stable and prolonged blood glucose control.

Metformin, a member of the biguanide class, works by reducing hepatic glucose production, enhancing insulin sensitivity, and increasing glucose uptake by peripheral tissues such as muscles. Unlike other antidiabetic agents, Metformin does not increase insulin secretion, which means the risk of hypoglycemia is minimal when used alone.

The 1000 mg SR tablet offers a higher-dose, convenient option for patients requiring more intensive glycemic control with fewer daily doses, improving treatment adherence and effectiveness.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Oramet-SR Tablet 1000 mg is indicated for:

• Type 2 diabetes mellitus: To achieve and maintain optimal glycemic control in adults.

• Combination therapy: Used alongside other oral antidiabetic drugs or insulin when diet, exercise, and monotherapy are insufficient.

• Prediabetes management: Under physician supervision, to reduce the risk of progression to type 2 diabetes.

It is not indicated for type 1 diabetes or diabetic ketoacidosis, which require insulin therapy.

Key Benefits

• Sustained-release formulation: Provides gradual drug release for stable blood sugar levels over the day.

• Effective glycemic control: Reduces fasting and postprandial glucose levels.

• Weight-neutral effect: Typically does not cause weight gain and may support modest weight reduction.

• Low risk of hypoglycemia: Safe when used alone as monotherapy.

• Convenient dosing: Once-daily dosing improves patient compliance and adherence.

Oramet-SR 1000 mg is particularly beneficial for patients who require higher-dose therapy without increasing the frequency of daily doses.

Dosage and Administration

• Adults: Usually 1 tablet once daily with the largest meal of the day, or as directed by a physician.

• Maximum total daily dose may be adjusted based on blood glucose response and treatment goals.

• Take the tablet whole with water; do not crush or chew, as this will affect the sustained-release mechanism.

• Gradual dose escalation may be required to minimize gastrointestinal side effects such as nausea, diarrhea, or abdominal discomfort.

• Monitor blood glucose levels regularly to ensure optimal glycemic control.

Precautions

• Avoid in patients with severe renal or hepatic impairment due to the risk of lactic acidosis, a rare but serious complication.

• Alcohol consumption should be limited, as it may increase the risk of lactic acidosis.

• Temporarily discontinue before surgery or imaging procedures using contrast dye, under physician guidance.

• Inform your doctor about all medications being taken to prevent drug interactions that may affect blood sugar.

• Regular monitoring of kidney function and glycemic levels is essential for safe treatment.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Oramet-SR Tablet 1000 mg is generally well tolerated. Common side effects include:

• Nausea, vomiting, or diarrhea

• Abdominal discomfort or bloating

• Mild metallic taste in the mouth

Rare but serious side effects may include lactic acidosis, especially in patients with kidney or liver problems. Seek immediate medical attention if symptoms such as rapid breathing, unusual fatigue, muscle pain, or abdominal pain occur.

Storage Instructions

• Store at below 25°C in a cool, dry place.

• Protect from light and moisture.

• Keep tablets in the original packaging until use.

• Keep out of reach of children.

• Do not use after the expiration date printed on the packaging.

Oramet-SR Tablet 1000 mg (Metformin Hydrochloride) is a safe, effective, and convenient treatment for type 2 diabetes. Its sustained-release formulation ensures steady blood sugar control, improved patient compliance, and long-term metabolic benefits when combined with diet, exercise, and regular monitoring.