Olmevas AM Tablet 5 mg+40 mg is a combination antihypertensive medicine containing Amlodipine Besilate, a calcium channel blocker, and Olmesartan Medoxomil, an angiotensin II receptor blocker (ARB). This higher-strength formulation is used for the management of moderate to severe hypertension in patients who require stronger blood pressure control. It provides effective 24-hour blood pressure reduction and helps reduce the risk of cardiovascular complications such as stroke, heart attack, and kidney damage.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Amlodipine Besilate equivalent to Amlodipine 5 mg
• Olmesartan Medoxomil 40 mg

Mechanism of Action

Amlodipine works by blocking calcium channels in vascular smooth muscle, leading to relaxation and widening of blood vessels, which reduces peripheral resistance and lowers blood pressure.

Olmesartan Medoxomil blocks angiotensin II type 1 (AT1) receptors, preventing vasoconstriction and aldosterone secretion. This results in further vasodilation and reduction in blood pressure.

Together, these two agents provide complementary mechanisms for stronger and more stable blood pressure control throughout the day.

Indications

Olmevas AM Tablet 5 mg+40 mg is indicated for:

• Essential hypertension (moderate to severe cases)
• Patients requiring combination therapy for uncontrolled blood pressure
• Reduction of cardiovascular risk in hypertensive patients
• Long-term management of high blood pressure

Dosage and Administration

• Take exactly as prescribed by a qualified physician.
• Usually taken once daily at the same time each day.
• Can be taken with or without food.
• Swallow the tablet whole with water; do not crush or chew.
• Do not discontinue or change dose without medical advice.

Benefits

• Strong dual-action blood pressure control
• Helps maintain stable 24-hour BP levels
• Reduces risk of heart attack, stroke, and kidney damage
• Effective for patients not controlled on single therapy
• Once-daily dosing improves compliance

Side Effects

Common side effects may include:

• Dizziness
• Headache
• Swelling of ankles or feet (peripheral edema)
• Fatigue
• Flushing

Serious but rare side effects:

• Excessive low blood pressure (hypotension)
• Kidney function impairment
• High potassium levels (hyperkalemia)
• Allergic reactions such as swelling or rash

Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Not recommended during pregnancy due to risk of fetal harm.
• Use cautiously in patients with liver, kidney, or heart disease.
• Regular monitoring of blood pressure and kidney function is recommended.
• Avoid potassium supplements unless prescribed.
• May cause dizziness; caution while driving or operating machinery.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Olmevas AM Tablet may interact with:

• Other antihypertensive medications
• Diuretics (water pills)
• Potassium supplements or potassium-sparing agents
• NSAIDs (may reduce antihypertensive effect)
• Lithium (increased toxicity risk)

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.