Nidocard Injection 50 mg/10 ml contains Nitroglycerin, a potent vasodilator used for the management of acute cardiovascular conditions requiring rapid therapeutic action. This intravenous (IV) infusion formulation allows precise and immediate delivery of nitroglycerin directly into the bloodstream, providing fast and controlled reduction of cardiac workload.

Nitroglycerin works by relaxing vascular smooth muscles, especially in veins and coronary arteries, leading to reduced preload and afterload. This decreases myocardial oxygen demand and improves blood flow to the heart muscle, alleviating ischemia and preventing complications such as angina, heart failure exacerbations, and acute myocardial infarction.

Nidocard Injection is typically used in hospital or clinical settings under strict medical supervision. It allows for titrated dosing, enabling healthcare providers to achieve the desired hemodynamic effect safely while minimizing risks such as hypotension or headache.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nidocard Injection 50 mg/10 ml is indicated for:

• Acute angina pectoris: Rapid relief of chest pain due to reduced coronary blood flow

• Acute heart failure: Management of pulmonary edema and associated symptoms by decreasing cardiac preload

• Hypertensive emergencies: Short-term control of elevated blood pressure in critical situations

• Acute myocardial infarction (AMI): Used as part of supportive therapy to reduce cardiac stress

• Perioperative use in cardiac surgery: To manage blood pressure and reduce myocardial oxygen demand

This IV infusion is intended for hospitalized patients or those requiring immediate cardiovascular intervention.

Key Benefits

• Rapid onset of action: IV administration allows immediate therapeutic effects

• Precise dosage control: Titration allows adjustment based on patient response

• Reduces heart workload: Dilates veins and coronary arteries to improve myocardial oxygen supply

• Prevents complications: Helps manage acute angina, heart failure exacerbations, and ischemic episodes

• Flexible clinical use: Suitable for multiple acute cardiovascular indications under supervision

Nidocard Injection provides a life-saving intervention in acute cardiac events, ensuring controlled vasodilation and symptom management.

Dosage and Administration

• Administer intravenously using a controlled infusion pump or IV line

• The starting dose is typically 5 mcg/min, titrated upward based on blood pressure, heart rate, and symptomatic response

• Maximum recommended infusion rates are 200 mcg/min, adjusted individually

• Continuous monitoring of blood pressure, heart rate, and oxygen saturation is essential during infusion

• Avoid abrupt discontinuation; taper slowly to prevent rebound angina or hypertension

• Use appropriate IV fluids and equipment to ensure compatibility and prevent precipitation

Dosage must be individualized based on patient condition and response, and administration should be strictly under medical supervision.

Precautions

• Use cautiously in patients with hypotension, severe anemia, increased intracranial pressure, or hypertrophic cardiomyopathy

• Monitor for hypotension, tachycardia, or headache, which are common during IV nitroglycerin therapy

• Avoid concurrent use with phosphodiesterase inhibitors (e.g., sildenafil, tadalafil) due to risk of severe hypotension

• Protect from light; discard unused portions of diluted solution after 24 hours

• Pregnancy and breastfeeding require careful consideration; use only if clearly indicated

Possible Side Effects

Nidocard Injection is generally well tolerated under clinical supervision. Common side effects may include:

• Headache and dizziness due to vasodilation

• Hypotension (low blood pressure) or lightheadedness

• Tachycardia (increased heart rate) as a reflex response

• Rare allergic reactions or methemoglobinemia with prolonged use

Close monitoring minimizes risk, and most side effects are dose-dependent and reversible.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store in a cool, dry place at 2–8°C, protected from light

• Do not freeze

• Keep out of reach of children

• Use immediately after preparation according to hospital protocol

Nidocard Injection 50 mg/10 ml (Nitroglycerin [IV Infusion]) is a critical care medication that provides rapid, controlled vasodilation for acute cardiovascular management, improving oxygen supply to the heart and relieving ischemic symptoms effectively.