Nabupain Tablet 750 mg contains Nabumetone, a nonsteroidal anti-inflammatory drug (NSAID) indicated for the relief of pain and inflammation associated with chronic joint disorders. It is commonly prescribed in conditions such as osteoarthritis and rheumatoid arthritis to help reduce pain, stiffness, and swelling.

Nabumetone is a prodrug that is converted in the liver into its active metabolite. This active form inhibits cyclooxygenase (COX) enzymes responsible for the production of prostaglandins, which are key mediators of inflammation and pain. By reducing prostaglandin synthesis, Nabupain provides effective and sustained symptom relief.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Strong anti-inflammatory action
  Helps reduce joint swelling, stiffness, and tenderness.

• Effective pain management
  Relieves mild to moderate pain associated with chronic inflammatory conditions.

• Flexible dosing option
  The 750 mg strength may be suitable for patients requiring higher therapeutic doses.

• Convenient administration
  Can be taken once or twice daily as prescribed.

Indications

Nabupain Tablet 750 mg is indicated for:

• Osteoarthritis

• Rheumatoid arthritis

• Other inflammatory musculoskeletal conditions as directed by a healthcare professional.

It supports improved joint mobility and enhances overall quality of life in patients with chronic joint disorders.

Dosage and Administration

• The usual adult dose ranges from 750 mg to 1500 mg per day, depending on severity and clinical response.

• May be taken once daily or divided into two doses.

• It is advisable to take the tablet with food or after meals to minimize gastrointestinal discomfort.

• Long-term therapy should be monitored by a healthcare provider.

Always follow the prescribed dosage and duration of treatment.

Mechanism of Action

After oral administration, Nabumetone is metabolized to its active form, which inhibits COX enzymes involved in prostaglandin production. This leads to reduced inflammation, pain, and swelling in affected joints.

Safety Information

Contraindications:

• Known hypersensitivity to nabumetone or other NSAIDs.

• History of NSAID-induced asthma or allergic reactions.

• Active gastrointestinal ulcer or bleeding.

Warnings and precautions:

• Prolonged use may increase the risk of gastrointestinal bleeding or ulceration.

• Use cautiously in patients with cardiovascular disease, hypertension, or renal impairment.

• Avoid use during the third trimester of pregnancy.

• Regular monitoring of liver and kidney function may be required during extended treatment.

Common side effects may include abdominal discomfort, indigestion, nausea, headache, and dizziness.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.