Nuprafen Tablet 500 mg contains Naproxen Sodium, a potent and widely used non-steroidal anti-inflammatory drug (NSAID). It is formulated to provide effective relief from pain, inflammation, swelling, and stiffness associated with a variety of acute and chronic musculoskeletal and inflammatory conditions. Due to its longer duration of action, Nuprafen 500 mg is often preferred for conditions requiring sustained pain control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Naproxen Sodium

• Strength: 500 mg per tablet

Therapeutic Class

• Non-steroidal Anti-Inflammatory Drug (NSAID)

Indications

Nuprafen Tablet 500 mg is indicated for the management and symptomatic relief of pain and inflammation in the following conditions:

• Rheumatoid arthritis

• Osteoarthritis

• Ankylosing spondylitis

• Acute gout

• Acute musculoskeletal pain

• Back pain and joint pain

• Tendinitis, bursitis, and sprains

• Dental pain and post-operative pain

• Dysmenorrhea (painful menstruation)

• Mild to moderate pain associated with inflammatory disorders

By controlling inflammation at the source, Nuprafen helps reduce pain intensity, improve joint mobility, and enhance daily functional activity.

Mechanism of Action

Naproxen Sodium exerts its therapeutic effects by inhibiting cyclooxygenase enzymes (COX-1 and COX-2). These enzymes are involved in the synthesis of prostaglandins, which are chemical mediators responsible for inflammation, pain, and fever. By reducing prostaglandin production, Nuprafen effectively alleviates pain, swelling, and stiffness while also helping to reduce fever.

Naproxen has a relatively long half-life compared to many other NSAIDs, allowing for prolonged anti-inflammatory and analgesic effects with fewer daily doses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

Nuprafen Tablet 500 mg should be taken orally with water, preferably after meals to minimize gastrointestinal irritation. Dosage depends on the severity of the condition and patient response:

• Typical adult dose: 500 mg once or twice daily

• Maximum daily dose should not exceed the physician’s recommendation

Dose adjustments may be required for elderly patients or individuals with renal, hepatic, or cardiovascular impairment. Long-term therapy should be conducted under medical supervision.

Side Effects

Like other NSAIDs, Nuprafen Tablet 500 mg may cause side effects, though many patients tolerate it well. Common side effects include:

• Gastric discomfort, indigestion, or heartburn

• Nausea or vomiting

• Headache or dizziness

Less common but serious side effects may include gastrointestinal ulceration or bleeding, fluid retention, elevated blood pressure, kidney dysfunction, or hypersensitivity reactions. Immediate medical attention is required if severe abdominal pain, black stools, or allergic symptoms occur.

Precautions and Warnings

• Use with caution in patients with a history of peptic ulcer disease or gastrointestinal bleeding

• Caution is advised in patients with cardiovascular disease, hypertension, kidney, or liver impairment

• Avoid use during the last trimester of pregnancy

• Concurrent use with other NSAIDs, anticoagulants, or corticosteroids should be monitored

• Alcohol consumption may increase the risk of gastrointestinal adverse effects

Storage

Store Nuprafen Tablet 500 mg in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.