Nabupain Tablet 500 mg contains Nabumetone, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation associated with various musculoskeletal and joint disorders. It is commonly prescribed for chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis.

Nabumetone is a prodrug that is converted in the liver to its active metabolite, which inhibits cyclooxygenase (COX) enzymes responsible for the production of prostaglandins. By reducing prostaglandin synthesis, it helps decrease pain, swelling, stiffness, and inflammation.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Effective pain relief
  Reduces mild to moderate pain associated with inflammatory joint conditions.

• Anti-inflammatory action
  Helps relieve swelling, joint stiffness, and discomfort.

• Once or twice daily dosing
  Offers convenient administration depending on physician recommendation.

• Suitable for long-term management
  Commonly used for chronic arthritis under medical supervision.

Indications

Nabupain Tablet 500 mg is indicated for:

• Osteoarthritis

• Rheumatoid arthritis

• Other inflammatory musculoskeletal conditions as prescribed by a healthcare provider.

It helps improve joint mobility and overall functional ability in patients suffering from chronic joint disorders.

Dosage and Administration

• The usual adult dose is 500 mg to 1000 mg daily, taken once or divided into two doses.

• May be taken with food to reduce gastrointestinal discomfort.

• Dosage should be individualized based on severity of symptoms and patient response.

• Long-term use should be monitored by a healthcare professional.

Always follow the prescribing physician’s instructions.

Mechanism of Action

Nabumetone is metabolized into its active form, which inhibits cyclooxygenase (COX) enzymes involved in prostaglandin production. This leads to reduced inflammation, pain, and swelling in affected tissues.

Safety Information

Contraindications:

• Hypersensitivity to nabumetone or other NSAIDs.

• History of NSAID-induced asthma, urticaria, or allergic reactions.

• Active peptic ulcer or gastrointestinal bleeding.

Warnings and precautions:

• May increase the risk of gastrointestinal bleeding, especially with long-term use.

• Use cautiously in patients with cardiovascular disease, hypertension, or kidney impairment.

• Avoid use during the third trimester of pregnancy.

• Monitor liver and kidney function during prolonged therapy.

Common side effects may include abdominal pain, indigestion, nausea, headache, and dizziness.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.