Evaglip Tablet 10 mg + 5 mg is a combination antidiabetic medicine that contains Empagliflozin and Linagliptin. It is used for the management of type 2 diabetes mellitus when diet, exercise, and single therapy are not sufficient to control blood sugar levels.
This dual-action therapy helps improve glycemic control through complementary mechanisms.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Composition
Each tablet contains:
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Empagliflozin 10 mg
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Linagliptin 5 mg
For oral administration.
Mechanism of Action
Evaglip works through two different pathways:
Empagliflozin (SGLT2 inhibitor)
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Reduces glucose reabsorption in the kidneys
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Promotes urinary excretion of excess glucose
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Helps lower blood sugar and body weight
Linagliptin (DPP-4 inhibitor)
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Increases incretin hormone levels
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Enhances insulin secretion in response to meals
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Reduces glucagon secretion from the liver
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Helps control post-meal blood sugar spikes
Indications
Evaglip Tablet is indicated for:
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Type 2 Diabetes Mellitus
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Patients inadequately controlled on monotherapy or diet/exercise alone
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As part of combination therapy to improve glycemic control
Dosage and Administration
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Usually taken once daily, with or without food
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Should be taken at the same time each day
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Dosage should be followed strictly as prescribed by a physician
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Not intended for type 1 diabetes or diabetic ketoacidosis
Benefits
Evaglip Tablet offers several benefits:
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Dual mechanism improves blood sugar control
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Helps reduce fasting and post-meal glucose levels
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May support modest weight reduction (due to empagliflozin)
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Low risk of hypoglycemia when used appropriately
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Convenient once-daily dosing
Possible Side Effects
Common side effects include:
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Urinary tract infection
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Increased urination
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Nasal congestion
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Headache
Less common side effects:
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Genital fungal infections
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Thirst or dehydration
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Mild gastrointestinal discomfort
Serious side effects:
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Diabetic Ketoacidosis
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Severe urinary infections
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Acute kidney problems (rare)
Precautions
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Maintain adequate hydration during treatment
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Monitor kidney function regularly
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Use cautiously in elderly patients or those with kidney impairment
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Not recommended in type 1 diabetes
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Inform doctor about all medications being taken
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Temporary discontinuation may be needed during surgery or severe illness
Drug Interactions
Evaglip may interact with:
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Diuretics (risk of dehydration)
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Insulin or sulfonylureas (increased risk of hypoglycemia)
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Other antidiabetic medications
Storage
Store in a cool, dry place below 30°C, protected from moisture and light. Keep out of reach of children.