Nabumax Tablet 1000 mg contains Nabumetone, a non-steroidal anti-inflammatory drug (NSAID) used for the management of pain and inflammation in various musculoskeletal and joint disorders. It helps reduce swelling, stiffness, and pain, improving joint movement and overall quality of life in patients with chronic inflammatory conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Nabumetone 1000 mg
• Dosage Form: Oral tablet

Indications

Nabumax Tablet 1000 mg is indicated for:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Musculoskeletal pain and inflammatory conditions
• Other inflammatory and degenerative joint disorders as prescribed by a physician

Mechanism of Action

Nabumetone is a non-acidic prodrug NSAID that is converted in the liver to its active metabolite. It works by:

• Inhibiting cyclooxygenase (COX) enzymes
• Reducing synthesis of prostaglandins, which mediate pain and inflammation
• Providing relief from pain, swelling, and stiffness

Its relatively COX-2 preferential activity may result in improved gastrointestinal tolerability compared to some traditional NSAIDs.

Dosage and Administration

• Usual adult dose: 1000 mg once daily, or as directed by a physician
• May be taken with food to minimize gastric discomfort
• Swallow whole with water
• Dose adjustment may be required based on severity of symptoms and patient response

Side Effects

Common side effects:

• Indigestion or stomach upset
• Nausea
• Headache
• Dizziness

Serious side effects:

• Gastrointestinal bleeding or ulceration
• Kidney function impairment
• Liver enzyme elevation
• Allergic reactions such as rash or swelling
• Increased cardiovascular risk with prolonged use

Precautions and Warnings

• Use cautiously in patients with a history of peptic ulcer disease or GI bleeding
• Avoid in severe renal or hepatic impairment
• Long-term use may increase risk of cardiovascular events
• Use the lowest effective dose for the shortest duration
• Caution in elderly patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Increased bleeding risk with anticoagulants (e.g., warfarin)
• Higher GI risk with other NSAIDs or corticosteroids
• May reduce effect of antihypertensive medications
• Caution when used with diuretics and lithium

Storage Conditions

• Store below 25°C
• Protect from moisture and light
• Keep out of reach of children.