Miragon Tablet 50 mg contains Mirabegron, a selective β3-adrenoceptor agonist indicated for the management of overactive bladder (OAB) with symptoms of urgency, frequency, and urge incontinence. By targeting β3 receptors in the bladder, Mirabegron helps relax the detrusor muscle during the storage phase, increasing bladder capacity and reducing urinary symptoms, thereby improving the patient’s quality of life.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Mirabegron 50 mg

Mechanism of Action

Mirabegron selectively stimulates β3-adrenoceptors in the bladder’s detrusor muscle. This relaxation of the muscle during the filling phase allows the bladder to store more urine and reduces episodes of urgency and incontinence. Unlike antimuscarinic drugs, Mirabegron avoids blocking acetylcholine receptors, which reduces the risk of dry mouth, constipation, and other anticholinergic side effects.

Indications

Miragon Tablet 50 mg is indicated for:

• Management of overactive bladder (OAB) in adults
• Reduction of urinary urgency, frequency, and urge incontinence
• Improvement in bladder storage capacity and overall bladder control

Dosage and Administration

• Recommended dose: 50 mg orally once daily
• Can be started at 25 mg and increased to 50 mg based on efficacy and tolerability
• Swallow tablets whole with water, with or without food
• Dose adjustment may be required in patients with moderate renal or hepatic impairment
• Regular follow-up is recommended to monitor efficacy and blood pressure

Benefits

• Significantly reduces urinary urgency, frequency, and urge incontinence
• Increases bladder capacity
• Well-tolerated with a lower risk of anticholinergic side effects
• Convenient once-daily oral dosing
• Improves patient comfort and quality of life

Side Effects

Common side effects:

• Elevated blood pressure
• Nasopharyngitis (cold-like symptoms)
• Headache
• Dizziness

Rare but serious side effects:

• Palpitations
• Severe hypertension
• Urinary retention

Precautions

• Monitor blood pressure regularly, especially in hypertensive patients
• Use with caution in patients with severe renal or hepatic impairment
• Not recommended in severe uncontrolled hypertension
• Inform your doctor of any cardiovascular conditions before starting treatment
• Avoid abrupt discontinuation without medical advice

Contraindications

• Hypersensitivity to Mirabegron or any excipients
• Severe uncontrolled hypertension

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• CYP2D6 substrates (Mirabegron may increase their plasma concentrations)
• Antihypertensive medications (monitor blood pressure)
• Drugs affecting renal excretion

Storage

• Store below 30°C
• Keep in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.