Mezest Tablet 160 mg contains Megestrol Acetate, a synthetic progestin used primarily for the management of hormone-responsive conditions and appetite stimulation in patients with cancer or chronic illnesses. It is commonly prescribed to treat cancer-related cachexia (weight loss and loss of appetite) and for certain gynecological conditions. Mezest helps improve appetite, promote weight gain, and support overall nutritional status in debilitated patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Megestrol Acetate 160 mg

Mechanism of Action

Megestrol Acetate is a progestational agent that works through multiple mechanisms:

• Acts on the hypothalamus to stimulate appetite
• Modulates hormone levels affecting metabolism and weight regulation
• Exhibits anti-estrogenic effects on certain tissues
• Helps improve fat and weight gain in cachectic patients

These combined effects make it useful in both oncological and gynecological conditions.

Indications

Mezest Tablet is indicated for:

• Cancer-associated anorexia and cachexia
• Unexplained weight loss in chronic illnesses (e.g., HIV/AIDS)
• Endometrial hyperplasia (as part of hormonal therapy)
• Palliative support in advanced disease-related wasting

Dosage and Administration

• Dosage is individualized based on patient condition and physician recommendation.
• Commonly taken orally once daily or in divided doses.
• Can be taken with or without food.
• Consistent daily use is recommended for best results in appetite and weight gain.

Benefits

• Improves appetite and food intake
• Promotes weight gain in cachectic patients
• Helps improve quality of life in chronic illness
• Useful supportive therapy in cancer care

Possible Side Effects

Common side effects may include:

• Increased appetite and weight gain
• Fluid retention or swelling
• Nausea
• Mood changes
• Fatigue

Less common but serious effects may include thromboembolic events or hormonal disturbances.

Precautions

• Use cautiously in patients with a history of blood clots
• Not recommended during pregnancy unless clearly necessary
• Monitor for signs of fluid retention or heart failure
• Use with caution in patients with diabetes or liver disease
• Regular medical supervision is advised during long-term use

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Megestrol Acetate may interact with:

• Anticoagulants (e.g., warfarin)
• Antidiabetic medications
• Other hormonal therapies
• Certain enzyme-inducing drugs

Always inform your healthcare provider about all medications being taken.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.