Meropen Injection 250 mg/vial contains Meropenem Trihydrate, a broad-spectrum carbapenem antibiotic used for the treatment of serious bacterial infections. It is highly effective against Gram-positive, Gram-negative, and anaerobic bacteria, including strains resistant to other antibiotics.

This injectable formulation allows for precise dosing and rapid bioavailability, making it suitable for hospitalized patients and severe infections requiring intravenous therapy. Meropen is commonly prescribed for complicated urinary tract infections, intra-abdominal infections, bacterial meningitis, and hospital-acquired pneumonia.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each vial contains:

• Meropenem Trihydrate 250 mg

Mechanism of Action

Meropenem is a beta-lactam antibiotic that:

• Inhibits bacterial cell wall synthesis

• Binds to penicillin-binding proteins (PBPs), causing bacterial cell death

• Effectively eliminates susceptible bacteria, including multi-drug resistant strains

Its broad-spectrum activity ensures rapid and effective treatment of severe infections.

Indications

Meropen Injection 250 mg/vial is indicated for:

• Complicated urinary tract infections (UTIs)

• Intra-abdominal infections, including peritonitis

• Bacterial meningitis

• Hospital-acquired pneumonia

• Severe systemic infections or sepsis caused by susceptible bacteria

Dosage and Administration

• Administer only under the supervision of a qualified healthcare professional

• Intravenous injection or infusion is recommended

• Typical adult dose: 250 mg every 8 hours, adjusted based on renal function and infection severity

• Infuse over 15–30 minutes or as directed by a physician

• Dose adjustment may be necessary in patients with impaired renal function

• Monitor patient response and laboratory parameters during therapy

Precautions

• Use with caution in patients with beta-lactam allergies

• Adjust dosing in renal impairment

• Monitor for superinfection or Clostridium difficile-associated diarrhea

• Avoid use for mild infections treatable with narrower-spectrum antibiotics

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Nausea, vomiting, or diarrhea

• Headache

• Injection site reactions

Rare but serious side effects may include:

• Severe allergic reactions (anaphylaxis)

• Seizures, particularly in high doses or patients with kidney impairment

• Blood disorders such as thrombocytopenia or neutropenia

• Clostridium difficile-associated diarrhea

Seek immediate medical attention if severe symptoms occur.

Storage

• Store below 25°C

• Keep in a dry place, protected from light

• Keep out of reach of children

• Reconstituted solution should be used immediately or stored as per guidelines.