Laxopride Tablet 2 mg contains Prucalopride Succinate, a selective serotonin (5-HT4) receptor agonist used for the treatment of chronic constipation. It is designed to enhance colonic motility and restore natural bowel function in patients who do not respond adequately to conventional laxatives.

Unlike traditional stimulant or bulk-forming laxatives, Prucalopride works by directly stimulating the enteric nervous system, providing a targeted and effective approach for long-term constipation management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Prucalopride Succinate
• Strength: 2 mg
• Dosage Form: Oral tablet

Mechanism of Action

Prucalopride is a highly selective 5-HT4 receptor agonist. It acts on serotonin receptors in the gastrointestinal tract, leading to:

• Enhanced colonic peristalsis (intestinal contractions)
• Improved bowel transit time
• Increased frequency of spontaneous bowel movements
• Restoration of normal defecation reflex

This mechanism helps improve bowel function without causing significant abdominal cramping or dependency commonly associated with stimulant laxatives.

Indications

Laxopride Tablet is indicated for:

• Chronic idiopathic constipation in adults
• Constipation resistant to conventional laxatives
• Functional bowel motility disorders
• Patients with long-term difficulty in bowel evacuation

Dosage and Administration

• Recommended dose: 2 mg once daily
• Can be taken with or without food
• Should be swallowed whole with water
• Dose adjustment may be required in patients with renal impairment or as directed by a physician
• Regular evaluation is recommended to assess treatment response

Benefits

• Promotes natural bowel movement
• Effective in chronic and difficult-to-treat constipation
• Non-habit forming when used as prescribed
• Improves stool frequency and consistency
• Works through a targeted receptor-based mechanism
• Suitable for long-term management under medical supervision

Side Effects

Common side effects may include:

• Headache
• Nausea
• Abdominal pain
• Diarrhea
• Dizziness

Less common but serious effects:

• Mood changes or depression (rare)
• Hypersensitivity reactions
• Severe gastrointestinal discomfort

Patients should report persistent or severe symptoms to a healthcare provider.

Precautions and Warnings

• Use only under medical supervision
• Not recommended in intestinal obstruction or perforation
• Caution in patients with severe renal impairment
• Monitor patients with a history of depression or psychiatric illness
• Avoid self-medication or prolonged unsupervised use
• Ensure adequate hydration and dietary fiber intake

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only if clearly necessary and prescribed
• Lactation: Not recommended unless advised by a physician
• Elderly: May be used with caution and monitoring
• Pediatric use: Safety and efficacy may vary; specialist advice required

Storage

• Store below 25°C
• Protect from moisture and direct sunlight
• Keep tightly closed in original packaging
• Keep out of reach of children.