Lanib Capsule 4 mg contains Lenvatinib Mesylate, an oral multikinase inhibitor used in the treatment of certain types of cancers. Lenvatinib acts by inhibiting multiple receptor tyrosine kinases involved in tumor growth, angiogenesis (formation of new blood vessels), and cancer progression. It is particularly effective in thyroid cancer, hepatocellular carcinoma (liver cancer), and selected cases of renal cell carcinoma.

Lanib Capsule 4 mg offers targeted therapy against cancer cells by disrupting the signaling pathways that promote tumor proliferation and blood vessel formation. This helps slow disease progression, reduce tumor growth, and improve overall survival in patients with advanced or unresectable cancers.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Lenvatinib Mesylate works as a multikinase inhibitor, targeting multiple receptors including:

• VEGFR1-3 (Vascular Endothelial Growth Factor Receptors): Reduces angiogenesis, limiting blood supply to tumors.

• FGFR1-4 (Fibroblast Growth Factor Receptors): Inhibits pathways involved in tumor growth and survival.

• PDGFRα, RET, KIT: Further interferes with cancer cell proliferation and tumor progression.

By blocking these signaling pathways, Lanib Capsule decreases tumor vascularization, inhibits cancer growth, and may enhance the effectiveness of other cancer therapies.

Indications

Lanib Capsule 4 mg is indicated for:

• Differentiated thyroid carcinoma refractory to radioactive iodine therapy

• Hepatocellular carcinoma in patients not suitable for surgical resection or transplantation

• Advanced renal cell carcinoma in combination with other anticancer agents, as directed by an oncologist

• Other cancers where Lenvatinib is indicated based on physician assessment and clinical guidelines

Dosage and Administration

• Lanib Capsule is administered orally, usually once daily, on an empty stomach or at least 1 hour before or 2 hours after meals.

• The starting dose and adjustments depend on the type of cancer, patient’s weight, liver and kidney function, and tolerance.

• Capsules should be swallowed whole with water; do not crush, chew, or split.

• Regular monitoring of blood pressure, liver function, kidney function, and blood counts is essential during therapy.

Precautions

Before taking Lanib Capsule 4 mg, inform your doctor if you have:

• High blood pressure (hypertension)

• Liver or kidney impairment

• Heart disease or history of cardiac issues

• Bleeding disorders

• Pregnancy or breastfeeding conditions

Patients should avoid self-medication, alcohol, and certain herbal supplements, as they may interfere with Lenvatinib’s efficacy or safety.

Use in Pregnancy and Lactation

Lenvatinib is contraindicated during pregnancy due to potential harm to the fetus. Effective contraception is advised during therapy and for a defined period after treatment. Breastfeeding should be discontinued during Lenvatinib therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Hypertension (high blood pressure)

• Fatigue and weakness

• Diarrhea or nausea

• Decreased appetite and weight loss

• Hand-foot syndrome (redness, pain, or swelling of hands and feet)

Serious side effects may include severe bleeding, liver toxicity, heart complications, or gastrointestinal perforation. Immediate medical attention is required if serious adverse events occur.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Lanib Capsule 4 mg provides targeted cancer therapy through inhibition of key signaling pathways, offering patients an advanced treatment option under careful oncological supervision.