Lamitan Tablet 50 mg contains Lasmiditan Hemisuccinate, a novel medication used for the acute treatment of migraine attacks with or without aura in adults. Unlike traditional migraine medications such as triptans, Lamitan belongs to a new class called ditans, which act selectively on serotonin (5-HT1F) receptors. This targeted mechanism provides rapid relief from migraine pain and associated symptoms such as nausea, photophobia, and sensitivity to sound, without causing significant vasoconstriction.

Lasmiditan is particularly beneficial for patients who cannot tolerate or are at risk from triptans, including those with cardiovascular conditions, because it does not constrict blood vessels. Lamitan Tablet 50 mg offers a convenient oral formulation for effective migraine management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Lasmiditan Hemisuccinate 50 mg

Mechanism of Action

Lasmiditan acts as a selective agonist of the 5-HT1F receptor, which is found on trigeminal nerve fibers in the brain. By activating these receptors, it:

• Inhibits the release of pro-inflammatory neuropeptides such as CGRP (Calcitonin Gene-Related Peptide)

• Reduces neurogenic inflammation

• Modulates pain signaling in the trigeminal pathway

Unlike triptans, Lasmiditan does not cause vasoconstriction, making it safer for patients with cardiovascular risk factors. The drug works quickly to alleviate migraine pain and associated neurological symptoms.

Indications

Lamitan Tablet 50 mg is indicated for:

• Acute treatment of migraine attacks with or without aura in adults

• Relief of associated migraine symptoms such as nausea, vomiting, light sensitivity (photophobia), and sound sensitivity (phonophobia)

• Suitable for patients who cannot use triptans due to cardiovascular risk

It is not indicated for the prevention of migraine attacks or for cluster headaches.

Dosage and Administration

• The recommended starting dose is 50 mg taken orally at the onset of migraine pain.

• A second dose may be taken at least 2 hours after the first dose if migraine symptoms persist, but the maximum recommended dose is 200 mg in 24 hours.

• Tablets should be swallowed whole with water and can be taken with or without food.

Patients should avoid driving or operating heavy machinery for at least 8 hours after taking Lamitan due to potential dizziness or sedation.

Benefits

• Rapid relief from migraine pain and associated symptoms

• Suitable for patients with cardiovascular risk who cannot use triptans

• Oral formulation is convenient and easy to administer

• Non-vasoconstrictive mechanism reduces cardiovascular concerns

• Improves quality of life by allowing patients to resume daily activities sooner

Precautions

• Not recommended for patients with severe hepatic impairment

• Caution in patients with a history of psychiatric disorders due to potential central nervous system effects

• Avoid alcohol while taking Lamitan

• Inform the doctor about other medications, particularly CNS depressants, as co-administration may enhance sedation

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Dizziness

• Sleepiness or sedation

• Nausea

• Fatigue

• Tingling or numbness (paresthesia)

Rare but serious effects may include:

• Severe allergic reactions

• Heart rhythm disturbances (uncommon)

Patients should seek immediate medical attention if they experience severe allergic reactions, chest pain, or pronounced neurological symptoms.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.