Hemorise Injection 500 mg/10 ml is an advanced intravenous iron preparation containing Ferric Carboxymaltose, indicated for the treatment of iron deficiency and iron deficiency anemia in adults and children who cannot tolerate oral iron therapy or require rapid iron replenishment. This formulation delivers a high dose of iron safely in a single administration, allowing for effective and convenient management of iron deficiency.

Iron deficiency is a common cause of anemia, fatigue, reduced cognitive performance, and impaired physical capacity. Hemorise Injection provides a controlled and bioavailable source of iron, which is essential for hemoglobin synthesis, oxygen transport, and overall cellular function.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 10 ml vial of Hemorise Injection contains:

• Ferric Carboxymaltose 500 mg

Ferric Carboxymaltose is a stable iron complex that allows for controlled release of iron, minimizing the risk of free iron toxicity and adverse reactions.

Mechanism of Action

Ferric Carboxymaltose acts as a source of elemental iron for the body. Once administered intravenously:

• The iron is rapidly taken up by the reticuloendothelial system.

• Iron is released in a controlled manner to bind to transferrin, the plasma protein responsible for iron transport.

• Transferrin delivers iron to the bone marrow, where it is incorporated into hemoglobin for red blood cell production.

• This replenishes iron stores efficiently, restoring normal hemoglobin levels and improving oxygen-carrying capacity.

The controlled release mechanism reduces the risk of free iron-mediated oxidative stress and allows for administration of larger doses compared to older IV iron formulations.

Indications

Hemorise Injection 500 mg/10 ml is indicated for:

• Iron deficiency anemia in adults and children (≥14 years)

• Patients intolerant to oral iron or with poor gastrointestinal absorption

• Rapid correction of iron deficiency in patients requiring immediate hemoglobin improvement

• Pre- or post-operative anemia management when oral supplementation is inadequate

Benefits

• Rapid and effective iron replenishment in a single or limited number of doses

• High-dose formulation reduces hospital visits and improves patient compliance

• Minimizes gastrointestinal side effects common with oral iron therapy

• Supports recovery from anemia, improving energy, cognition, and physical performance

• Suitable for patients with chronic conditions like chronic kidney disease or inflammatory bowel disease

Dosage and Administration

Hemorise Injection should be administered intravenously under medical supervision. The recommended single dose is 500 mg diluted in 100 ml of 0.9% sodium chloride, infused over at least 15 minutes. Dosing may be repeated based on hemoglobin levels, body iron deficit, and physician assessment. Continuous monitoring for hypersensitivity reactions during and after infusion is essential.

Precautions

• Administer only under supervision of a healthcare professional trained in managing anaphylactic reactions.

• Monitor for signs of hypersensitivity, hypotension, or allergic reactions during and after infusion.

• Use with caution in patients with a history of hypersensitivity to iron preparations.

• Not recommended for patients with iron overload or hemochromatosis.

• Ensure correct calculation of total iron deficit before administration.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Mild headache, dizziness, or nausea

• Injection site reactions such as pain, swelling, or erythema

• Transient hypotension

• Rarely, hypersensitivity or anaphylactic reactions

Most side effects are mild and transient when infusion protocols are followed carefully.

Storage

Store below 30°C in a dry place, protected from light. Do not freeze. Keep out of reach of children.

Hemorise Injection 500 mg/10 ml provides a safe, effective, and convenient option for rapid correction of iron deficiency anemia, improving hemoglobin levels and patient quality of life under medical supervision.