Insul Injection 30% + 70% is a premixed insulin formulation containing Regular Human Insulin (30%) and Isophane Insulin (NPH insulin, 70%). It is used for the management of diabetes mellitus to help control high blood glucose levels and maintain long-term glycemic balance. This combination provides both rapid onset and intermediate duration of action, making it suitable for routine diabetes management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Regular Insulin Human 30%
• Isophane Insulin Human (NPH) 70%
• Strength: 40 IU/ml

Mechanism of Action

• Regular Insulin (Short-acting): Helps reduce post-meal blood glucose by facilitating rapid uptake of glucose into cells.
• Isophane Insulin (Intermediate-acting): Provides a slower, prolonged release of insulin to maintain basal glucose control between meals and overnight.

Together, they mimic natural insulin activity by controlling both immediate and long-term blood sugar levels.

Indications

Insul Injection is indicated for:

• Type 1 diabetes mellitus
• Type 2 diabetes mellitus when oral antidiabetic drugs are insufficient
• Gestational diabetes (when diet control is inadequate)
• Control of hyperglycemia in hospitalized patients
• Insulin-dependent diabetes requiring mixed insulin therapy

Dosage and Administration

• Administered via subcutaneous injection only
• Dosage is individualized based on blood glucose levels, diet, and physician guidance
• Usually injected 30–45 minutes before meals (depending on medical advice)
• Injection sites include abdomen, thigh, or upper arm
• Site rotation is recommended to prevent lipodystrophy

Possible Side Effects

Common side effects may include:

• Hypoglycemia (low blood sugar)
• Weight gain
• Injection site redness or swelling
• Lipodystrophy (fat changes at injection site)

Less common but serious effects:

• Severe hypoglycemia leading to confusion, seizures, or loss of consciousness
• Allergic reactions
• Electrolyte imbalance (low potassium levels)

Precautions

• Regular blood glucose monitoring is essential
• Do not skip meals after insulin injection
• Alcohol may increase risk of hypoglycemia
• Dose adjustment may be required during illness, stress, or changes in diet
• Use with caution in patients with kidney or liver impairment

Contraindications

• Hypoglycemia (low blood sugar episodes)
• Known hypersensitivity to insulin or any formulation component

Drug Interactions

• Oral antidiabetic drugs (may enhance hypoglycemic effect)
• Corticosteroids (may increase blood glucose levels)
• Beta-blockers (may mask symptoms of hypoglycemia)
• Diuretics and thyroid medications may also affect glucose control

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store in a refrigerator (2°C to 8°C)
• Do not freeze
• Protect from direct heat and sunlight
• Once in use, may be kept at room temperature for a limited period as directed

Important Notes

Insul Injection 30% + 70% is an effective premixed insulin therapy designed to simplify diabetes management. Proper dose timing, diet control, and regular monitoring are essential for safe and effective use. Always use under strict medical supervision.