Hydrogest Injection 250 mg/ml contains Hydroxyprogesterone Caproate, a synthetic form of the natural hormone progesterone. This injectable formulation is primarily used in obstetrics and gynecology to support pregnancy and manage certain menstrual disorders. Hydroxyprogesterone Caproate helps maintain uterine quiescence, reduces the risk of preterm labor, and regulates hormonal imbalances, making it a vital therapy for women at risk of premature birth or progesterone deficiency.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Hydrogest Injection 250 mg/ml is indicated for:

• Prevention of preterm birth – For women with a history of spontaneous preterm delivery.

• Progesterone supplementation – To support pregnancy in cases of luteal phase deficiency.

• Management of gynecological disorders – Conditions such as irregular menstruation or abnormal uterine bleeding caused by progesterone deficiency.

Mechanism of Action

Hydroxyprogesterone Caproate is a synthetic progestogen that works by:

• Supporting the uterine lining – Promotes endometrial stability to support implantation and early pregnancy.

• Maintaining uterine quiescence – Reduces uterine contractions, lowering the risk of premature labor.

• Regulating hormonal balance – Helps correct progesterone deficiencies that affect menstrual cycles or pregnancy maintenance.

Dosage and Administration

• Recommended dose: Typically, 250 mg administered intramuscularly once weekly or as prescribed by a healthcare professional.

• Administration: Inject intramuscularly, usually in the gluteal region. Should only be administered by a trained healthcare provider.

• Monitoring: Regular follow-up with a physician is required to assess efficacy and safety, especially during pregnancy.

Precautions and Warnings

• Pregnancy use: Only administer under medical supervision. Avoid use in women with unexplained vaginal bleeding.

• Allergies: Not recommended for patients hypersensitive to Hydroxyprogesterone Caproate or other progestogens.

• Medical conditions: Caution in patients with liver dysfunction, thromboembolic disorders, or history of cardiovascular disease.

• Injection site reactions: Mild pain or irritation may occur; proper technique reduces the risk.

Side Effects

Common side effects may include:

• Injection site reactions (pain, redness, or swelling)

• Mild headache or dizziness

• Nausea

• Breast tenderness

Rare but serious side effects include allergic reactions, blood clots, or significant hormonal changes, requiring immediate medical attention.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store Hydrogest Injection 250 mg/ml in a cool, dry place at 2–8°C, protected from light. Do not freeze. Keep out of reach of children.

Conclusion

Hydrogest Injection 250 mg/ml by SK Pharma is a safe and effective therapy for supporting pregnancy and managing progesterone-related gynecological conditions. By maintaining uterine stability and regulating hormonal balance, it helps reduce the risk of preterm birth and supports reproductive health under medical supervision. Proper administration and regular monitoring ensure optimal efficacy and safety.