FXR Tablet contains Obeticholic Acid 10 mg, a selective farnesoid X receptor (FXR) agonist used in the treatment of chronic liver diseases. It works by regulating bile acid production, reducing liver inflammation, and improving liver function. This medicine is primarily used in conditions involving bile acid dysregulation and progressive liver damage.

Obeticholic Acid is prescribed under specialist supervision, especially by hepatologists, as part of long-term liver disease management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

FXR Tablet 10 mg is indicated for:

• Primary biliary cholangitis (PBC)
• Chronic cholestatic liver disease
• Bile acid-related liver dysfunction
• Adjunct therapy in liver fibrosis management
• Patients with inadequate response to ursodeoxycholic acid (UDCA)

Mechanism of Action

Obeticholic Acid works by activating FXR receptors:

• Stimulates farnesoid X receptor (FXR) in the liver and intestines
• Reduces bile acid synthesis in the liver
• Increases bile acid transport and clearance
• Decreases liver inflammation and fibrosis progression
• Improves overall liver biochemical profile

Dosage & Administration

• Usual dose: 10 mg once daily or as prescribed by physician
• May be taken with or without food
• Dose may be adjusted based on liver function and tolerance
• Regular monitoring of liver enzymes is required
• Long-term therapy under specialist supervision is necessary

Side Effects

Common side effects may include:

• Itching (pruritus)
• Fatigue
• Abdominal discomfort
• Rash
• Dizziness
• Elevated cholesterol levels

Serious side effects may include worsening liver function in advanced disease.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use only under hepatologist supervision
• Not recommended in advanced decompensated liver disease
• Monitor liver function tests regularly
• Caution in patients with severe liver impairment
• Use during pregnancy only if clearly necessary
• Inform physician about all ongoing medications

Storage

• Store below 25°C in a cool and dry place
• Protect from moisture and light
• Keep in original packaging
• Keep out of reach of children.