Fluzin Tablet 5 mg contains Flunarizine, a selective calcium channel blocker with antihistaminic properties, widely used for the prevention of migraine attacks and the management of vestibular disorders such as vertigo and balance disturbances. Flunarizine works by inhibiting the excessive influx of calcium ions into vascular smooth muscle and neurons, which stabilizes blood vessels in the brain and reduces neuronal hyperexcitability, key factors in migraine pathophysiology.

Fluzin is primarily prescribed for prophylactic treatment rather than acute migraine attacks. Its unique mechanism also helps improve cerebral blood flow and reduce the frequency, intensity, and duration of headaches. Additionally, it provides symptomatic relief for patients experiencing vertigo associated with vestibular disorders, improving balance and reducing dizziness episodes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fluzin Tablet 5 mg is indicated for:

• Prophylaxis of migraine attacks in adults and adolescents

• Vestibular disorders associated with vertigo, dizziness, and motion sickness

• Peripheral vascular disorders where calcium channel modulation is beneficial

• Symptomatic relief in patients with balance disturbances

It should be used under the supervision of a healthcare professional, as it is intended for long-term prophylaxis rather than immediate relief.

Mechanism of Action

• Calcium channel blockade: Flunarizine selectively inhibits the influx of calcium ions into smooth muscle and neuronal cells, reducing hyperexcitability and vasoconstriction in cerebral blood vessels.

• Neuroprotective effects: It stabilizes neuronal membranes, helping prevent the cascade of events that trigger migraine attacks.

• Histamine H1 antagonism: Mild antihistaminic activity may contribute to its anti-vertigo effects.

• Vascular modulation: Improves cerebral blood flow and reduces neuronal ischemia, helping prevent migraine onset and reducing vestibular symptoms.

Dosage and Administration

Dosage should be individualized based on patient needs and tolerability:

• Adults: 5 mg orally once daily, preferably at bedtime to reduce daytime drowsiness

• Elderly patients: Start with the lowest effective dose; monitor for side effects

• Children and adolescents: Use only under strict medical supervision

• Take the tablet with water; can be taken with or without food

• Treatment is usually long-term, and patients may require several weeks before optimal benefit is observed

Benefits and Features

• Effective prophylactic treatment for migraine

• Reduces the frequency, intensity, and duration of headaches

• Helps manage vertigo and balance disorders

• Convenient oral tablet for once-daily administration

• Provides neuroprotective and vascular stabilizing effects

Side Effects

Fluzin Tablet 5 mg is generally well tolerated, but some patients may experience:

• Drowsiness or fatigue (most common, usually mild)

• Weight gain with prolonged use

• Gastrointestinal disturbances: nausea, constipation

• Rarely, extrapyramidal symptoms such as tremor or stiffness

• Mood changes or depressive symptoms in susceptible individuals

Patients should report any persistent or severe side effects to their healthcare provider.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Avoid use in patients with depressive disorders or history of significant psychiatric illness

• Use with caution in elderly patients and those with pre-existing neurological or cardiovascular conditions

• May cause drowsiness; avoid driving or operating machinery until individual tolerance is known

• Not recommended during pregnancy and lactation unless prescribed

• Regular monitoring is advised during long-term therapy

Storage Conditions

Store Fluzin Tablet 5 mg in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.

Fluzin Tablet 5 mg is a safe and effective option for migraine prophylaxis and management of vertigo, providing improved quality of life for patients suffering from recurrent headaches or vestibular disorders.