Fluzin Tablet 10 mg contains Flunarizine, a selective calcium channel blocker with antihistaminic properties, primarily used for the prevention of migraine attacks and the management of vestibular disorders such as vertigo and balance disturbances. Flunarizine works by inhibiting the excessive influx of calcium ions into vascular smooth muscle and neurons, which stabilizes cerebral blood vessels and reduces neuronal hyperexcitability. This action helps prevent the cascade of events that lead to migraine attacks and improves symptoms of dizziness associated with vestibular dysfunction.

Fluzin 10 mg is indicated for patients who require a higher dose for effective migraine prophylaxis or in cases where 5 mg daily is insufficient. The tablet form ensures convenient once-daily oral administration and provides sustained therapeutic levels for long-term management of migraine and vestibular symptoms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fluzin Tablet 10 mg is indicated for:

• Prophylaxis of migraine attacks in adults and adolescents

• Vestibular disorders such as vertigo, dizziness, and motion sickness

• Peripheral vascular disorders where calcium channel modulation is beneficial

• Symptomatic relief for patients with balance disturbances

It is intended for long-term preventive therapy rather than acute treatment of migraine attacks.

Mechanism of Action

• Calcium channel blockade: Flunarizine selectively inhibits calcium influx into smooth muscle and neurons, preventing vasoconstriction and reducing neuronal hyperexcitability.

• Neuroprotective effects: Stabilizes neuronal membranes, reducing the likelihood of migraine onset.

• Histamine H1 receptor antagonism: Provides mild antihistaminic effects that help relieve vertigo and motion sickness.

• Vascular modulation: Enhances cerebral blood flow and reduces ischemia-related symptoms.

Dosage and Administration

Dosage should be individualized based on the patient’s clinical needs and tolerability:

• Adults: 10 mg orally once daily, preferably at bedtime to reduce daytime drowsiness

• Elderly patients: Start with the lowest effective dose and monitor for side effects

• Adolescents: Use only under medical supervision

• Take the tablet with water, with or without food

• Long-term treatment is usually required, and several weeks may be necessary before optimal benefit is observed

Benefits and Features

• Highly effective for migraine prophylaxis, reducing frequency, severity, and duration of attacks

• Improves vertigo and balance disorders in vestibular conditions

• Convenient once-daily oral dosing

• Provides neuroprotective and vascular stabilizing effects

• Suitable for patients requiring a higher dose for optimal therapeutic effect

Side Effects

Fluzin Tablet 10 mg is generally well tolerated. Potential side effects include:

• Drowsiness or fatigue (most common, especially at higher doses)

• Weight gain with prolonged use

• Gastrointestinal disturbances: nausea, constipation

• Rarely, extrapyramidal symptoms such as tremor, rigidity, or stiffness

• Mood changes or depressive symptoms, especially in susceptible individuals

Patients should report persistent or severe side effects to their healthcare provider promptly.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Avoid use in patients with depression or psychiatric disorders

• Use cautiously in elderly patients and those with cardiovascular or neurological conditions

• May cause drowsiness; avoid driving or operating machinery until tolerance is known

• Not recommended during pregnancy and lactation unless prescribed

• Regular monitoring is advised during long-term therapy

Storage Conditions

Store Fluzin Tablet 10 mg in a cool, dry place below 30°C, protected from direct sunlight and moisture. Keep out of reach of children.

Fluzin Tablet 10 mg is an effective preventive treatment for migraine and vestibular disorders, offering higher-dose therapy for optimal symptom control, improved quality of life, and long-term safety with consistent oral dosing.