Fluclox Capsule 500 mg contains Flucloxacillin Sodium, a narrow-spectrum penicillin antibiotic highly effective against Gram-positive bacteria, particularly Staphylococcus aureus, including penicillinase-producing strains. It is commonly prescribed for moderate to severe bacterial infections requiring higher antibiotic coverage.

Flucloxacillin works by inhibiting bacterial cell wall synthesis, causing bacterial cell death and promoting rapid recovery from infections. The 500 mg capsule provides a convenient oral option for adults and adolescents who need a higher therapeutic dose.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fluclox Capsule 500 mg is indicated for the treatment of:

• Skin and soft tissue infections (cellulitis, boils, abscesses)
• Wound infections
• Bone and joint infections (osteomyelitis)
• Respiratory tract infections (tonsillitis, pneumonia)
• Ear infections (otitis media)
• Prophylactic use in surgery prone to Staphylococcus infections

Dosage and Administration

• Adults: 500 mg every 6 hours, depending on infection severity.
• Children: Dose calculated based on body weight and clinical condition.
• Take the capsule on an empty stomach—at least 30 minutes before or 2 hours after meals—with a full glass of water.
• Complete the full prescribed course, even if symptoms improve earlier.

Mechanism of Action

Flucloxacillin is a beta-lactam antibiotic that:

• Binds to penicillin-binding proteins (PBPs)
• Inhibits bacterial cell wall synthesis
• Causes cell lysis and bacterial death

This mechanism ensures effective clearance of Gram-positive infections, including penicillinase-producing Staphylococcus aureus.

Precautions

• Use cautiously in patients with a history of penicillin allergy.
• Monitor liver function in prolonged use, as rare cases of cholestatic jaundice have been reported.
• Prolonged therapy may lead to superinfection by resistant organisms.
• Adequate hydration is recommended to prevent kidney complications.

Contraindications

Do not use Fluclox Capsule 500 mg in:

• Patients with hypersensitivity to penicillin or other beta-lactam antibiotics
• History of severe allergic reactions to Flucloxacillin

Side Effects

Common side effects:

• Nausea and vomiting
• Diarrhea
• Abdominal discomfort
• Skin rash or itching

Rare but serious side effects:

• Severe allergic reactions (anaphylaxis, angioedema)
• Liver dysfunction or cholestatic jaundice
• Severe diarrhea due to Clostridium difficile infection

Seek immediate medical attention if serious side effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral anticoagulants (e.g., warfarin)
• Probenecid may reduce renal excretion, increasing Flucloxacillin levels
• Live bacterial vaccines may be less effective

Always inform your healthcare provider about all medications being taken.

Storage

• Store below 25–30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.