Fixolin Tablet 400 mg contains Doxophylline, a bronchodilator from the methylxanthine group, used in the long-term management of respiratory disorders associated with airway obstruction. It is commonly prescribed for patients with bronchial asthma and chronic obstructive pulmonary disease, where it helps improve airflow, reduce breathing difficulty, and enhance overall respiratory function.

Doxophylline is a newer generation xanthine derivative with a better safety profile compared to traditional theophylline. It provides effective bronchodilation without significant stimulation of the central nervous system or cardiovascular system, making Fixolin Tablet suitable for prolonged use under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fixolin Tablet 400 mg is indicated for:

• Bronchial asthma

• Chronic obstructive pulmonary disease

• Chronic bronchitis

• Emphysema

• Other respiratory conditions associated with bronchospasm

Pharmacological Action

Doxophylline works by inhibiting phosphodiesterase enzymes, leading to increased levels of cyclic AMP in bronchial smooth muscle. This results in relaxation of airway muscles and bronchodilation. Additionally, it has anti-inflammatory properties and improves diaphragmatic contractility, which further supports easier breathing. Unlike theophylline, Doxophylline has minimal affinity for adenosine receptors, reducing the risk of cardiac and central nervous system side effects.

Dosage and Administration

• The dosage is determined by the severity of the condition and patient response.

• Fixolin Tablet is administered orally and may be taken with or without food.

• Patients should follow the prescribed dosing schedule and avoid dose escalation without medical advice.

• Long-term therapy should be monitored by a healthcare professional.

Benefits

• Effective bronchodilation and improved airflow

• Better safety and tolerability compared to traditional xanthines

• Suitable for long-term management of asthma and COPD

• Reduced risk of cardiac stimulation

• Convenient oral tablet formulation

Side Effects

Common side effects may include:

• Nausea

• Vomiting

• Headache

• Gastric discomfort

• Mild dizziness

These effects are usually transient and dose-related. Serious adverse reactions are uncommon when used at recommended doses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with cardiac disorders, peptic ulcer disease, or liver impairment

• Not recommended during pregnancy and breastfeeding unless clearly necessary

• Avoid excessive caffeine intake during therapy

• Regular medical follow-up is advised during prolonged treatment

Drug Interactions

Doxophylline may interact with certain antibiotics, anticonvulsants, and other bronchodilators. Patients should inform their physician about all concomitant medications.

Storage

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Fixolin Tablet 400 mg is an effective and well-tolerated bronchodilator that helps relieve bronchospasm, improve breathing, and support better quality of life in patients with chronic respiratory conditions.